Complete preclinical evaluation of the novel antibody mimetic Nanofitin-IRDye800CW for diverse non-invasive diagnostic applications in the management of HER-2 positive tumors

Complete preclinical evaluation of the novel antibody mimetic Nanofitin-IRDye800CW for diverse non-invasive diagnostic applications in the management of HER-2 positive tumors

Abstract There are well-known limitations associated to the use of antibodies in the non-invasive detection of HER-2 expression. In fact, current procedures recommended for diagnostic purposes of HER-2 status are still invasive techniques. Here, a novel, smaller diagnostic probe, the anti-HER-2 Nano...

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Bibliographic Details
Main Authors: Margherita Iaboni, Federico Crivellin, Francesca Arena, Francesca La Cava, Alessia Cordaro, Francesco Stummo, Daniele Faletto, Simon Huet, Leo Candela, Jessy Pedrault, Eugenia R. Zanella, Andrea Bertotti, Francesco Blasi, Alessandro Maiocchi, Luisa Poggi, Erika Reitano
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Nanofitin
HER-2
Near-infrared
Optical imaging
Online Access:https://doi.org/10.1038/s41598-025-93696-w
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