Gastrointestinal System Involvement in Pediatric Patients with Acute SARS-CoV-2 Infection
Objective: The prevalence of gastrointestinal symptoms in coronavirus disease-2019 (COVID-19) has been reported widely. In this study, the prevalence of gastrointestinal system (GIS) involvement in pediatric COVID-19 and its effect on prognosis were investigated. Methods: Children (aged 0-18 years)...
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Galenos Publishing House
2022-12-01
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| Series: | Medeniyet Medical Journal |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-79674 |
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| author | Ozlem KALAYCIK SENGUL Burcin BEKEN Zehra OZTURK Seyma OZPINAR Gizem OZKAN Gizem GUNGOR |
| author_facet | Ozlem KALAYCIK SENGUL Burcin BEKEN Zehra OZTURK Seyma OZPINAR Gizem OZKAN Gizem GUNGOR |
| author_sort | Ozlem KALAYCIK SENGUL |
| collection | DOAJ |
| description | Objective: The prevalence of gastrointestinal symptoms in coronavirus disease-2019 (COVID-19) has been reported widely. In this study, the prevalence of gastrointestinal system (GIS) involvement in pediatric COVID-19 and its effect on prognosis were investigated.
Methods: Children (aged 0-18 years) with acute COVID-19 were included in the study. The patients were grouped according to system involvement: isolated respiratory system (RS), isolated GIS, and combination of both (RS+GIS). These groups were compared in terms of demographic data, clinical characteristics, laboratory and imaging findings, and hospitalization.
Results: A total of 223 pediatric patients were included in the study. Of these patients, 19 were asymptomatic, 12 were diagnosed with a multisystem inflammatory syndrome in children, 21 had chronic disorders that may affect disease severity, and 27 had symptoms not related to RS or GIS. The remaining 144 patients were classified according to system involvement: 79 (35.4%), 14 (6.3%), and 51 (22.9%) had isolated RS, isolated GIS, and RS+GIS involvement, respectively. The GIS group was much younger than the RS group (median, 30 and 150 months, respectively, p=0.006). Three patients from the RS group were followed in the intensive care unit (ICU). Moreover, 17 (21.5%) and 4 (7.8%) patients from the RS group had severe-critical respiratory symptoms, in the RS+GIS group had severe-critical respiratory symptoms (p=0.039).
Conclusions: Our study showed that GIS involvement in children with COVID-19 is more prevalent than RS involvement in the younger age group. Respiratory symptom severity and ICU admission also decreased with accompanying GIS involvement. GIS involvement |
| format | Article |
| id | doaj-art-3efa117f21704389b31bb7282af5ba3f |
| institution | Kabale University |
| issn | 2149-2042 2149-4606 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Medeniyet Medical Journal |
| spelling | doaj-art-3efa117f21704389b31bb7282af5ba3f2025-01-30T07:07:34ZengGalenos Publishing HouseMedeniyet Medical Journal2149-20422149-46062022-12-0137433233810.4274/MMJ.galenos.2022.79674MEDJ-79674Gastrointestinal System Involvement in Pediatric Patients with Acute SARS-CoV-2 InfectionOzlem KALAYCIK SENGUL0Burcin BEKEN1Zehra OZTURK2Seyma OZPINAR3Gizem OZKAN4Gizem GUNGOR5University of Health Sciences Turkey, Kanuni Sultan Suleyman Training and Research Hospital, Clinic of Pediatric Gastroenterology, Hepatology and Nutrition, Istanbul, TurkeyUniversity of Health Sciences Turkey, Kanuni Sultan Suleyman Training and Research Hospital, Clinic of Pediatric Allergy and Immunology, Istanbul, TurkeyUniversity of Health Sciences Turkey, Kanuni Sultan Suleyman Training and Research Hospital, Clinic of Pediatrics, Istanbul, TurkeyUniversity of Health Sciences Turkey, Kanuni Sultan Suleyman Training and Research Hospital, Clinic of Pediatrics, Istanbul, TurkeyUniversity of Health Sciences Turkey, Kanuni Sultan Suleyman Training and Research Hospital, Clinic of Pediatrics, Istanbul, TurkeyUniversity of Health Sciences Turkey, Kanuni Sultan Suleyman Training and Research Hospital, Clinic of Pediatrics, Istanbul, TurkeyObjective: The prevalence of gastrointestinal symptoms in coronavirus disease-2019 (COVID-19) has been reported widely. In this study, the prevalence of gastrointestinal system (GIS) involvement in pediatric COVID-19 and its effect on prognosis were investigated. Methods: Children (aged 0-18 years) with acute COVID-19 were included in the study. The patients were grouped according to system involvement: isolated respiratory system (RS), isolated GIS, and combination of both (RS+GIS). These groups were compared in terms of demographic data, clinical characteristics, laboratory and imaging findings, and hospitalization. Results: A total of 223 pediatric patients were included in the study. Of these patients, 19 were asymptomatic, 12 were diagnosed with a multisystem inflammatory syndrome in children, 21 had chronic disorders that may affect disease severity, and 27 had symptoms not related to RS or GIS. The remaining 144 patients were classified according to system involvement: 79 (35.4%), 14 (6.3%), and 51 (22.9%) had isolated RS, isolated GIS, and RS+GIS involvement, respectively. The GIS group was much younger than the RS group (median, 30 and 150 months, respectively, p=0.006). Three patients from the RS group were followed in the intensive care unit (ICU). Moreover, 17 (21.5%) and 4 (7.8%) patients from the RS group had severe-critical respiratory symptoms, in the RS+GIS group had severe-critical respiratory symptoms (p=0.039). Conclusions: Our study showed that GIS involvement in children with COVID-19 is more prevalent than RS involvement in the younger age group. Respiratory symptom severity and ICU admission also decreased with accompanying GIS involvement. GIS involvementhttps://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-79674childcovid-19gastrointestinal systemsars-cov-2disease severity |
| spellingShingle | Ozlem KALAYCIK SENGUL Burcin BEKEN Zehra OZTURK Seyma OZPINAR Gizem OZKAN Gizem GUNGOR Gastrointestinal System Involvement in Pediatric Patients with Acute SARS-CoV-2 Infection Medeniyet Medical Journal child covid-19 gastrointestinal system sars-cov-2 disease severity |
| title | Gastrointestinal System Involvement in Pediatric Patients with Acute SARS-CoV-2 Infection |
| title_full | Gastrointestinal System Involvement in Pediatric Patients with Acute SARS-CoV-2 Infection |
| title_fullStr | Gastrointestinal System Involvement in Pediatric Patients with Acute SARS-CoV-2 Infection |
| title_full_unstemmed | Gastrointestinal System Involvement in Pediatric Patients with Acute SARS-CoV-2 Infection |
| title_short | Gastrointestinal System Involvement in Pediatric Patients with Acute SARS-CoV-2 Infection |
| title_sort | gastrointestinal system involvement in pediatric patients with acute sars cov 2 infection |
| topic | child covid-19 gastrointestinal system sars-cov-2 disease severity |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-79674 |
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