Evaluation of Renal Function in Pregnant Women with Malaria: A Case-Control Study in a Mesoendemic Area
Background. Malaria is known to have devastating effects on mortality in tropical and subtropical regions with the effect being magnified in people with weakened immunity such as those in pregnancy. We assessed the effect of malaria on renal function of pregnant women receiving antenatal care in a m...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2017-01-01
|
| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2017/6030943 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850216348780593152 |
|---|---|
| author | Justice Afrifa Samuel Essien-Baidoo Albert Baffour Gyau Richard Kobina Dadzie Ephraim |
| author_facet | Justice Afrifa Samuel Essien-Baidoo Albert Baffour Gyau Richard Kobina Dadzie Ephraim |
| author_sort | Justice Afrifa |
| collection | DOAJ |
| description | Background. Malaria is known to have devastating effects on mortality in tropical and subtropical regions with the effect being magnified in people with weakened immunity such as those in pregnancy. We assessed the effect of malaria on renal function of pregnant women receiving antenatal care in a mesoendemic area of Ghana. Methodology. A case-control study that enrolled a total of 100 pregnant women (50 with confirmed gestational malaria as cases and 50 without malaria as controls). Sociodemographic characteristics, obstetric history (obtained with a questionnaire), urea, creatinine, sodium, and potassium were analyzed using a chemistry automated analyzer. Results. Plasma urea and creatinine were significantly increased (P=0.0003 and P<0.0001, resp.) among cases compared to the controls. Also the levels of urea (P=0.033), creatinine (P=0.032), and parasitaemia (0.016) were significantly increased with increasing gestational age. Conclusion. Malaria has a significant impact on renal function (most importantly, urea and creatinine) and is also significantly associated with increasing gestational age among our study participants. |
| format | Article |
| id | doaj-art-3ed2dd2a3e4642eba4e4af0cd2003ef0 |
| institution | OA Journals |
| issn | 1687-9589 1687-9597 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-3ed2dd2a3e4642eba4e4af0cd2003ef02025-08-20T02:08:20ZengWileyObstetrics and Gynecology International1687-95891687-95972017-01-01201710.1155/2017/60309436030943Evaluation of Renal Function in Pregnant Women with Malaria: A Case-Control Study in a Mesoendemic AreaJustice Afrifa0Samuel Essien-Baidoo1Albert Baffour Gyau2Richard Kobina Dadzie Ephraim3Department of Medical Laboratory Technology, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, GhanaDepartment of Medical Laboratory Technology, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, GhanaDepartment of Medical Laboratory Technology, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, GhanaDepartment of Medical Laboratory Technology, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, GhanaBackground. Malaria is known to have devastating effects on mortality in tropical and subtropical regions with the effect being magnified in people with weakened immunity such as those in pregnancy. We assessed the effect of malaria on renal function of pregnant women receiving antenatal care in a mesoendemic area of Ghana. Methodology. A case-control study that enrolled a total of 100 pregnant women (50 with confirmed gestational malaria as cases and 50 without malaria as controls). Sociodemographic characteristics, obstetric history (obtained with a questionnaire), urea, creatinine, sodium, and potassium were analyzed using a chemistry automated analyzer. Results. Plasma urea and creatinine were significantly increased (P=0.0003 and P<0.0001, resp.) among cases compared to the controls. Also the levels of urea (P=0.033), creatinine (P=0.032), and parasitaemia (0.016) were significantly increased with increasing gestational age. Conclusion. Malaria has a significant impact on renal function (most importantly, urea and creatinine) and is also significantly associated with increasing gestational age among our study participants.http://dx.doi.org/10.1155/2017/6030943 |
| spellingShingle | Justice Afrifa Samuel Essien-Baidoo Albert Baffour Gyau Richard Kobina Dadzie Ephraim Evaluation of Renal Function in Pregnant Women with Malaria: A Case-Control Study in a Mesoendemic Area Obstetrics and Gynecology International |
| title | Evaluation of Renal Function in Pregnant Women with Malaria: A Case-Control Study in a Mesoendemic Area |
| title_full | Evaluation of Renal Function in Pregnant Women with Malaria: A Case-Control Study in a Mesoendemic Area |
| title_fullStr | Evaluation of Renal Function in Pregnant Women with Malaria: A Case-Control Study in a Mesoendemic Area |
| title_full_unstemmed | Evaluation of Renal Function in Pregnant Women with Malaria: A Case-Control Study in a Mesoendemic Area |
| title_short | Evaluation of Renal Function in Pregnant Women with Malaria: A Case-Control Study in a Mesoendemic Area |
| title_sort | evaluation of renal function in pregnant women with malaria a case control study in a mesoendemic area |
| url | http://dx.doi.org/10.1155/2017/6030943 |
| work_keys_str_mv | AT justiceafrifa evaluationofrenalfunctioninpregnantwomenwithmalariaacasecontrolstudyinamesoendemicarea AT samuelessienbaidoo evaluationofrenalfunctioninpregnantwomenwithmalariaacasecontrolstudyinamesoendemicarea AT albertbaffourgyau evaluationofrenalfunctioninpregnantwomenwithmalariaacasecontrolstudyinamesoendemicarea AT richardkobinadadzieephraim evaluationofrenalfunctioninpregnantwomenwithmalariaacasecontrolstudyinamesoendemicarea |