Effects of testosterone undecanoate treatment on serum biochemical parameters in new zealand rabbits
<b>Aim: </b>Anabolic androgenic steroids (AAS), used to treat various diseases, are also doping substances for athletes to improve their sportive performance. The aim of this study is to evaluate some serum biochemical parameters in New Zealand rabbits treated with long-term Testosterone...
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| Format: | Article |
| Language: | English |
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Selcuk University Press
2024-06-01
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| Series: | Eurasian Journal of Veterinary Sciences |
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| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=1450 |
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| author | Beyza Suvarikli Alan Avni Camgoz Mustafa Orhun Dayan Seyfullah Haliloglu Nida Karakaya |
| author_facet | Beyza Suvarikli Alan Avni Camgoz Mustafa Orhun Dayan Seyfullah Haliloglu Nida Karakaya |
| author_sort | Beyza Suvarikli Alan |
| collection | DOAJ |
| description | <b>Aim: </b>Anabolic androgenic steroids (AAS), used to treat various diseases, are
also doping substances for athletes to improve their sportive performance.
The aim of this study is to evaluate some serum biochemical parameters in
New Zealand rabbits treated with long-term Testosterone Undecanoate (TU).<p>
<b>Materials and Methods: </b>In the present study, 21 male New Zealand rabbits
aged 5-6 weeks were divided into 3 groups; control, castor oil group, and TU
group (in which TU was diluted in castor oil). In the Castor oil and TU diluted
in castor oil (10 mg/kg) were injected intramuscularly in 0.1 ml for 6 weeks,
5 days a week in the related groups.<p>
<b>Results:</b> The results of the study, in which a total of 22 biochemical
parameters were evaluated, showed that aspartate aminotransferase,
amylase, triglyceride, total cholesterol, total protein, creatinine, uric acid,
phosphate, potassium, sodium, calcium, and glucose levels were statistically
significantly higher in the TU group than in the control and castor oil groups,
and high-density lipoprotein levels were significantly lower in the other
groups compared to the control group.<p>
<b>Conclusion:</b> In conclusion, it can be stated that TU administration
may adversely affect serum biochemistry in New Zealand rabbits and
multidisciplinary studies with different testosterone analogues should be
performed. |
| format | Article |
| id | doaj-art-3e9f003cb4ea43efbe7875fff212210c |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-3e9f003cb4ea43efbe7875fff212210c2025-02-03T11:25:37ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-19532024-06-0140281871450Effects of testosterone undecanoate treatment on serum biochemical parameters in new zealand rabbitsBeyza Suvarikli Alan0Avni Camgoz1Mustafa Orhun Dayan2Seyfullah Haliloglu3Nida Karakaya4Selçuk University, Faculty of Veterinary, Department of Biochemistry, Konya, TürkiyeSelçuk University, Faculty of Veterinary, Department of Biochemistry, Konya, TürkiyeSelçuk University, Faculty of Veterinary, Department of Anatomy, Konya, TürkiyeSelçuk University, Faculty of Veterinary, Department of Biochemistry, Konya, TürkiyeBatman University, Vocational School of Technical Sciences, Department of Veterinary Medicine, Batman, Türkiye<b>Aim: </b>Anabolic androgenic steroids (AAS), used to treat various diseases, are also doping substances for athletes to improve their sportive performance. The aim of this study is to evaluate some serum biochemical parameters in New Zealand rabbits treated with long-term Testosterone Undecanoate (TU).<p> <b>Materials and Methods: </b>In the present study, 21 male New Zealand rabbits aged 5-6 weeks were divided into 3 groups; control, castor oil group, and TU group (in which TU was diluted in castor oil). In the Castor oil and TU diluted in castor oil (10 mg/kg) were injected intramuscularly in 0.1 ml for 6 weeks, 5 days a week in the related groups.<p> <b>Results:</b> The results of the study, in which a total of 22 biochemical parameters were evaluated, showed that aspartate aminotransferase, amylase, triglyceride, total cholesterol, total protein, creatinine, uric acid, phosphate, potassium, sodium, calcium, and glucose levels were statistically significantly higher in the TU group than in the control and castor oil groups, and high-density lipoprotein levels were significantly lower in the other groups compared to the control group.<p> <b>Conclusion:</b> In conclusion, it can be stated that TU administration may adversely affect serum biochemistry in New Zealand rabbits and multidisciplinary studies with different testosterone analogues should be performed.http://eurasianjvetsci.org/pdf.php3?id=1450serumrabbittestosterone undecanoate |
| spellingShingle | Beyza Suvarikli Alan Avni Camgoz Mustafa Orhun Dayan Seyfullah Haliloglu Nida Karakaya Effects of testosterone undecanoate treatment on serum biochemical parameters in new zealand rabbits Eurasian Journal of Veterinary Sciences serum rabbit testosterone undecanoate |
| title | Effects of testosterone undecanoate treatment on serum biochemical parameters in new zealand rabbits |
| title_full | Effects of testosterone undecanoate treatment on serum biochemical parameters in new zealand rabbits |
| title_fullStr | Effects of testosterone undecanoate treatment on serum biochemical parameters in new zealand rabbits |
| title_full_unstemmed | Effects of testosterone undecanoate treatment on serum biochemical parameters in new zealand rabbits |
| title_short | Effects of testosterone undecanoate treatment on serum biochemical parameters in new zealand rabbits |
| title_sort | effects of testosterone undecanoate treatment on serum biochemical parameters in new zealand rabbits |
| topic | serum rabbit testosterone undecanoate |
| url | http://eurasianjvetsci.org/pdf.php3?id=1450 |
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