Exploring the potential of Carica Papaya Leaf Extract: a perspective on its effectiveness in ameliorating thrombocytopenia in dengue patients
Background: Dengue fever (DF) is endemic in Pakistan, posing health risks. Recent flooding in 2022 and strong monsoon rains in 2024 have increased the possibility of an epidemic. It is an infectious disease having potentially severe outcomes including thrombocytopenia.Discussion: Carica Papaya Leaf...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Infection Ecology & Epidemiology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/20008686.2025.2456055 |
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| author | Maliha Khalid Muhammad Saad Khan Erum Siddiqui Aminath Waafira |
| author_facet | Maliha Khalid Muhammad Saad Khan Erum Siddiqui Aminath Waafira |
| author_sort | Maliha Khalid |
| collection | DOAJ |
| description | Background: Dengue fever (DF) is endemic in Pakistan, posing health risks. Recent flooding in 2022 and strong monsoon rains in 2024 have increased the possibility of an epidemic. It is an infectious disease having potentially severe outcomes including thrombocytopenia.Discussion: Carica Papaya Leaf Extract (CPLE) has emerged as an off-label treatment option, showing promising results in increasing platelet counts and reducing hospital stays. However, a critical assessment of existing research reveals methodological flaws, hindering specific recommendations.Conclusion: This perspective advocates for comprehensive research to evaluate the risks and benefits of CPLE as a potential remedy for thrombocytopenia associated with dengue fever. A robust investigation will inform clinical practice and guide healthcare decisions, contributing to improved patient outcomes in dengue-endemic areas. |
| format | Article |
| id | doaj-art-3e939513afd84c57bbb8abf54e27023b |
| institution | Kabale University |
| issn | 2000-8686 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Infection Ecology & Epidemiology |
| spelling | doaj-art-3e939513afd84c57bbb8abf54e27023b2025-01-23T17:31:58ZengTaylor & Francis GroupInfection Ecology & Epidemiology2000-86862025-12-0115110.1080/20008686.2025.2456055Exploring the potential of Carica Papaya Leaf Extract: a perspective on its effectiveness in ameliorating thrombocytopenia in dengue patientsMaliha Khalid0Muhammad Saad Khan1Erum Siddiqui2Aminath Waafira3Department of Medicine, Jinnah Sindh Medical University, Karachi, PakistanDepartment of Medicine, Jinnah Sindh Medical University, Karachi, PakistanDepartment of Medicine, Jinnah Sindh Medical University, Karachi, PakistanSchool of Medicine, The Maldives National University, Malé, MaldivesBackground: Dengue fever (DF) is endemic in Pakistan, posing health risks. Recent flooding in 2022 and strong monsoon rains in 2024 have increased the possibility of an epidemic. It is an infectious disease having potentially severe outcomes including thrombocytopenia.Discussion: Carica Papaya Leaf Extract (CPLE) has emerged as an off-label treatment option, showing promising results in increasing platelet counts and reducing hospital stays. However, a critical assessment of existing research reveals methodological flaws, hindering specific recommendations.Conclusion: This perspective advocates for comprehensive research to evaluate the risks and benefits of CPLE as a potential remedy for thrombocytopenia associated with dengue fever. A robust investigation will inform clinical practice and guide healthcare decisions, contributing to improved patient outcomes in dengue-endemic areas.https://www.tandfonline.com/doi/10.1080/20008686.2025.2456055ThrombocytopeniadengueCarica Papaya Leaf Extract |
| spellingShingle | Maliha Khalid Muhammad Saad Khan Erum Siddiqui Aminath Waafira Exploring the potential of Carica Papaya Leaf Extract: a perspective on its effectiveness in ameliorating thrombocytopenia in dengue patients Infection Ecology & Epidemiology Thrombocytopenia dengue Carica Papaya Leaf Extract |
| title | Exploring the potential of Carica Papaya Leaf Extract: a perspective on its effectiveness in ameliorating thrombocytopenia in dengue patients |
| title_full | Exploring the potential of Carica Papaya Leaf Extract: a perspective on its effectiveness in ameliorating thrombocytopenia in dengue patients |
| title_fullStr | Exploring the potential of Carica Papaya Leaf Extract: a perspective on its effectiveness in ameliorating thrombocytopenia in dengue patients |
| title_full_unstemmed | Exploring the potential of Carica Papaya Leaf Extract: a perspective on its effectiveness in ameliorating thrombocytopenia in dengue patients |
| title_short | Exploring the potential of Carica Papaya Leaf Extract: a perspective on its effectiveness in ameliorating thrombocytopenia in dengue patients |
| title_sort | exploring the potential of carica papaya leaf extract a perspective on its effectiveness in ameliorating thrombocytopenia in dengue patients |
| topic | Thrombocytopenia dengue Carica Papaya Leaf Extract |
| url | https://www.tandfonline.com/doi/10.1080/20008686.2025.2456055 |
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