Inflammatory Monocytes Are Rapidly Recruited to the Post-Ischaemic Liver in Patients Undergoing Liver Transplantation and Cytokines Associated with Their Activation Correlate with Graft Outcomes

Inflammatory Monocytes Are Rapidly Recruited to the Post-Ischaemic Liver in Patients Undergoing Liver Transplantation and Cytokines Associated with Their Activation Correlate with Graft Outcomes

Liver ischaemia–reperfusion (IR) injury remains a major cause of morbidity and mortality following liver transplantation and resection. CD4+ T cells have been shown to play a key role in murine models; however, there is currently a lack of data that support their role in human patients. <i>Met...

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Bibliographic Details
Main Authors: Francis P. Robertson, Antonia O. Cuff, Victoria Male, Graham P. Wright, Laura J. Pallett, Barry J. Fuller, Brian R. Davidson
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Current Issues in Molecular Biology
Subjects:
liver transplantation
ischaemia–reperfusion injury
CD4+ T cells
inflammatory monocytes
Online Access:https://www.mdpi.com/1467-3045/47/1/49
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