The Minute Virus of Canines (MVC) Activates the RhoA/ROCK1/MLC2 Signal Transduction Pathway Resulting in the Dissociation of Tight Junctions and Facilitating Occludin-Mediated Viral Infection

The Minute Virus of Canines (MVC) Activates the RhoA/ROCK1/MLC2 Signal Transduction Pathway Resulting in the Dissociation of Tight Junctions and Facilitating Occludin-Mediated Viral Infection

The Minute Virus of Canines (MVC), belonging to the genus <i>Bocaparvovirus</i> within the family <i>Parvoviridae</i>, is associated with enteritis and embryonic infection in neonatal canines. Viral attachment to host cells is a critical step in infection, and viral protein 2...

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Bibliographic Details
Main Authors: Xiang Ren, Zhiping Hei, Kai Ji, Yan Yan, Chuchu Tian, Yin Wei, Yuning Sun
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Microorganisms
Subjects:
MVC
protein interaction
RhoA/ROCK1/MLC2 signaling pathway
virus entry
VP2 protein
Online Access:https://www.mdpi.com/2076-2607/13/3/695
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