Case Report: severe pulmonary hypertension in a child with micronutrient deficiency
We describe the rare case of a previously healthy seven year-old boy, with an acute clinical onset of severe pulmonary hypertension. He recovered rapidly after vitamin supplementation. Patient history showed a highly selective food intake in the context of autistic features. Thiamine deficiency seem...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2025.1478889/full |
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| author | Laure Pache-Wannaz Cristiana Voicu Laurence Boillat Nicole Sekarski |
| author_facet | Laure Pache-Wannaz Cristiana Voicu Laurence Boillat Nicole Sekarski |
| author_sort | Laure Pache-Wannaz |
| collection | DOAJ |
| description | We describe the rare case of a previously healthy seven year-old boy, with an acute clinical onset of severe pulmonary hypertension. He recovered rapidly after vitamin supplementation. Patient history showed a highly selective food intake in the context of autistic features. Thiamine deficiency seemed to be the predominant causing factor aggravated by moderate iron deficiency and supposed vitamin C deficiency. Dietary impact on pulmonary pressures is still poorly understood, but it seems that micronutrient deficiency could be a rare cause of pulmonary hypertension. Relatively frequent in developing countries and mostly in infants, thiamine deficiency should not be forgotten as a potential etiology in the differential diagnosis when patient dietary history is particular. |
| format | Article |
| id | doaj-art-3e8241da4d564ae3be81eb88203e9d71 |
| institution | Kabale University |
| issn | 2296-2360 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj-art-3e8241da4d564ae3be81eb88203e9d712025-01-31T06:40:15ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602025-01-011310.3389/fped.2025.14788891478889Case Report: severe pulmonary hypertension in a child with micronutrient deficiencyLaure Pache-Wannaz0Cristiana Voicu1Laurence Boillat2Nicole Sekarski3Pediatric Cardiology, Women-Mother-Child Department, Lausanne University Hospital and University of Lausanne, Lausanne, SwitzerlandPediatric Cardiology, Women-Mother-Child Department, Lausanne University Hospital and University of Lausanne, Lausanne, SwitzerlandPediatric Intensive Care Unit, Women-Mother-Child Department, Lausanne University Hospital and University of Lausanne, Lausanne, SwitzerlandPediatric Cardiology, Women-Mother-Child Department, Lausanne University Hospital and University of Lausanne, Lausanne, SwitzerlandWe describe the rare case of a previously healthy seven year-old boy, with an acute clinical onset of severe pulmonary hypertension. He recovered rapidly after vitamin supplementation. Patient history showed a highly selective food intake in the context of autistic features. Thiamine deficiency seemed to be the predominant causing factor aggravated by moderate iron deficiency and supposed vitamin C deficiency. Dietary impact on pulmonary pressures is still poorly understood, but it seems that micronutrient deficiency could be a rare cause of pulmonary hypertension. Relatively frequent in developing countries and mostly in infants, thiamine deficiency should not be forgotten as a potential etiology in the differential diagnosis when patient dietary history is particular.https://www.frontiersin.org/articles/10.3389/fped.2025.1478889/fullcase reportpulmonary hypertensionthiamine deficiencymicronutrient deficiencyvitamin supplementationselective food behavior |
| spellingShingle | Laure Pache-Wannaz Cristiana Voicu Laurence Boillat Nicole Sekarski Case Report: severe pulmonary hypertension in a child with micronutrient deficiency Frontiers in Pediatrics case report pulmonary hypertension thiamine deficiency micronutrient deficiency vitamin supplementation selective food behavior |
| title | Case Report: severe pulmonary hypertension in a child with micronutrient deficiency |
| title_full | Case Report: severe pulmonary hypertension in a child with micronutrient deficiency |
| title_fullStr | Case Report: severe pulmonary hypertension in a child with micronutrient deficiency |
| title_full_unstemmed | Case Report: severe pulmonary hypertension in a child with micronutrient deficiency |
| title_short | Case Report: severe pulmonary hypertension in a child with micronutrient deficiency |
| title_sort | case report severe pulmonary hypertension in a child with micronutrient deficiency |
| topic | case report pulmonary hypertension thiamine deficiency micronutrient deficiency vitamin supplementation selective food behavior |
| url | https://www.frontiersin.org/articles/10.3389/fped.2025.1478889/full |
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