RNAi dynamics in Juvenile Fasciola spp. Liver flukes reveals the persistence of gene silencing in vitro.

RNAi dynamics in Juvenile Fasciola spp. Liver flukes reveals the persistence of gene silencing in vitro.

<h4>Background</h4>Fasciola spp. liver fluke cause pernicious disease in humans and animals. Whilst current control is unsustainable due to anthelmintic resistance, gene silencing (RNA interference, RNAi) has the potential to contribute to functional validation of new therapeutic targets...

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Main Authors: Paul McVeigh, Erin M McCammick, Paul McCusker, Russell M Morphew, Angela Mousley, Abbas Abidi, Khalid M Saifullah, Raman Muthusamy, Ravikumar Gopalakrishnan, Terry W Spithill, John P Dalton, Peter M Brophy, Nikki J Marks, Aaron G Maule
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0003185
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