From Placenta to Polycystic Ovarian Syndrome: The Role of Adipokines
Adipokines are cytokines produced mainly by adipose tissue, besides many other tissues such as placenta, ovaries, peripheral-blood mononuclear cells, liver, muscle, kidney, heart, and bone marrow. Adipokines play a significant role in the metabolic syndrome and in cardiovascular diseases, have impli...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2016/4981916 |
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| author | Chiara Sartori Pietro Lazzeroni Silvia Merli Viviana Dora Patianna Francesca Viaroli Francesca Cirillo Sergio Amarri Maria Elisabeth Street |
| author_facet | Chiara Sartori Pietro Lazzeroni Silvia Merli Viviana Dora Patianna Francesca Viaroli Francesca Cirillo Sergio Amarri Maria Elisabeth Street |
| author_sort | Chiara Sartori |
| collection | DOAJ |
| description | Adipokines are cytokines produced mainly by adipose tissue, besides many other tissues such as placenta, ovaries, peripheral-blood mononuclear cells, liver, muscle, kidney, heart, and bone marrow. Adipokines play a significant role in the metabolic syndrome and in cardiovascular diseases, have implications in regulating insulin sensitivity and inflammation, and have significant effects on growth and reproductive function. The objective of this review was to analyze the functions known today of adiponectin, leptin, resistin, and visfatin from placenta throughout childhood and adolescence. It is well known now that their serum concentrations during pregnancy and lactation have long-term effects beyond the fetus and newborn. With regard to puberty, adipokines are involved in the regulation of the relationship between nutritional status and normal physiology or disorders of puberty and altered gonadal function, as, for example, premature pubarche and polycystic ovarian syndrome (PCOS). Cytokines are involved in the maturation of oocytes and in the regular progression of puberty and pregnancy. |
| format | Article |
| id | doaj-art-3e8038d5c9464ea48729595331774278 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-3e8038d5c9464ea487295953317742782025-02-03T05:57:12ZengWileyMediators of Inflammation0962-93511466-18612016-01-01201610.1155/2016/49819164981916From Placenta to Polycystic Ovarian Syndrome: The Role of AdipokinesChiara Sartori0Pietro Lazzeroni1Silvia Merli2Viviana Dora Patianna3Francesca Viaroli4Francesca Cirillo5Sergio Amarri6Maria Elisabeth Street7Department of Paediatrics, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, ItalyDepartment of Paediatrics, University Hospital of Parma, Parma, ItalyDepartment of Paediatrics, University Hospital of Parma, Parma, ItalyDepartment of Paediatrics, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, ItalyDepartment of Paediatrics, University Hospital of Parma, Parma, ItalyDepartment of Paediatrics, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, ItalyDepartment of Paediatrics, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, ItalyDepartment of Paediatrics, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, ItalyAdipokines are cytokines produced mainly by adipose tissue, besides many other tissues such as placenta, ovaries, peripheral-blood mononuclear cells, liver, muscle, kidney, heart, and bone marrow. Adipokines play a significant role in the metabolic syndrome and in cardiovascular diseases, have implications in regulating insulin sensitivity and inflammation, and have significant effects on growth and reproductive function. The objective of this review was to analyze the functions known today of adiponectin, leptin, resistin, and visfatin from placenta throughout childhood and adolescence. It is well known now that their serum concentrations during pregnancy and lactation have long-term effects beyond the fetus and newborn. With regard to puberty, adipokines are involved in the regulation of the relationship between nutritional status and normal physiology or disorders of puberty and altered gonadal function, as, for example, premature pubarche and polycystic ovarian syndrome (PCOS). Cytokines are involved in the maturation of oocytes and in the regular progression of puberty and pregnancy.http://dx.doi.org/10.1155/2016/4981916 |
| spellingShingle | Chiara Sartori Pietro Lazzeroni Silvia Merli Viviana Dora Patianna Francesca Viaroli Francesca Cirillo Sergio Amarri Maria Elisabeth Street From Placenta to Polycystic Ovarian Syndrome: The Role of Adipokines Mediators of Inflammation |
| title | From Placenta to Polycystic Ovarian Syndrome: The Role of Adipokines |
| title_full | From Placenta to Polycystic Ovarian Syndrome: The Role of Adipokines |
| title_fullStr | From Placenta to Polycystic Ovarian Syndrome: The Role of Adipokines |
| title_full_unstemmed | From Placenta to Polycystic Ovarian Syndrome: The Role of Adipokines |
| title_short | From Placenta to Polycystic Ovarian Syndrome: The Role of Adipokines |
| title_sort | from placenta to polycystic ovarian syndrome the role of adipokines |
| url | http://dx.doi.org/10.1155/2016/4981916 |
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