Signatures of lower respiratory tract microbiome in children with severe community-acquired pneumonia using shotgun metagenomic sequencing

Signatures of lower respiratory tract microbiome in children with severe community-acquired pneumonia using shotgun metagenomic sequencing

Background: Severe community-acquired pneumonia was associated with high morbidity and mortality in children. However, species-level microbiome of lower airway was sparse, and we used shotgun metagenomic next-generation sequencing to explore microbial signatures. Methods: We conducted a prospective...

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Bibliographic Details
Main Authors: Ting-Yu Yen, Ching Hsu, Ni-Chung Lee, Chao-Szu Wu, Hsin Wang, Kuan-Yi Lee, Chia-Ray Lin, Chun-Yi Lu, Mo-Li Tsai, Tzu-Yu Liu, Che Lin, Chien-Yu Chen, Luan-Yin Chang, Feipei Lai, Li-Min Huang
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Microbiology, Immunology and Infection
Subjects:
Children
Community-acquired pneumonia
Lower respiratory tract
Metagenomic sequencing
Microbiome
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118224002172
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