The quinoline framework and related scaffolds in natural products with anti-Leishmania properties

For almost one hundred years, the quinoline heterocycle has been recognized as a privileged pharmacophore in anti-Leishmania agents. Early on, the action of compounds with this scaffold, found in some natural alkaloids, was tested against different Leishmania stages and strains. Different structural...

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Bibliographic Details
Main Authors: Gloria Yaluff, Leídi Herrera, Miriam Soledad Rolón, Celeste Vega, Hugo Cerecetto
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Chemistry
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Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2025.1571067/full
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