Massage‐Mimicking Nanosheets Mechanically Reorganize Inter‐organelle Contacts to Restore Mitochondrial Functions in Parkinson's Disease

Massage‐Mimicking Nanosheets Mechanically Reorganize Inter‐organelle Contacts to Restore Mitochondrial Functions in Parkinson's Disease

Abstract Parkinson's disease (PD) is exacerbated by dysfunction of inter‐organelle contact, which depends on cellular responses to the mechanical microenvironment and can be regulated by external mechanical forces. Delivering dynamic mechanical forces to neural cells proves challenging due to t...

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Main Authors: Tianqi Li, Liwen Huang, Chenxiao Guo, Jing Ren, Xi Chen, Yachu Ke, Zengyu Xun, Wenzhuo Hu, Yilin Qi, Heping Wang, Zhongying Gong, Xing‐Jie Liang, Xue Xue
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
inter‐organelle contacts
mechanical stimulation
mitochondria
nanosheets
Parkinson's disease
Online Access:https://doi.org/10.1002/advs.202413376
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