Relation of Malnutrition and Nosocomical Infections in Cancer Patients in Hospital: An Observational Study
Aim. To investigate the relation between malnutrition and nosocomial infections (NI) in hospitalized cancer patients. Methods. This observational, cross-sectional, noninterventional, descriptive study was conducted in a 500-bed university hospital in Valencia (Spain). Adult cancer patients admitted...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Journal of Nutrition and Metabolism |
| Online Access: | http://dx.doi.org/10.1155/2022/5232480 |
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| author | Bianca Tabita Muresan Martín Núñez‐Abad Ana Artero Jaime Rios Rios Alberto Jacobo Cunquero-Tomás Vega Iranzo Javier Garrido Ana Jiménez-Portilla Carlos Camps Herrero Carlos J. Sánchez Juan |
| author_facet | Bianca Tabita Muresan Martín Núñez‐Abad Ana Artero Jaime Rios Rios Alberto Jacobo Cunquero-Tomás Vega Iranzo Javier Garrido Ana Jiménez-Portilla Carlos Camps Herrero Carlos J. Sánchez Juan |
| author_sort | Bianca Tabita Muresan |
| collection | DOAJ |
| description | Aim. To investigate the relation between malnutrition and nosocomial infections (NI) in hospitalized cancer patients. Methods. This observational, cross-sectional, noninterventional, descriptive study was conducted in a 500-bed university hospital in Valencia (Spain). Adult cancer patients admitted to the oncology ward were consecutively enrolled regardless of their nutritional status between November 2019 and March 2020. Patients were nutritionally assessed 24 to 48 hours after admission. Body weight, height and BMI, body composition through measurement of bioelectrical impedance analysis (BIA), and muscle strength and functionality using hand grip strength (HGS) were prospectively collected. The diagnosis of malnutrition and sarcopenia was assessed using the Global Leadership Initiative on Malnutrition (GLIM) criteria and the European Working Group on Sarcopenia in Older People (EWGSOP) criteria, respectively. Patients were followed up during their hospital stay or outpatient oncology visits to identify possible NI. Results. A total of 107 patients were included in this study (mean age 66 years; 66.4% were men). The most frequent reason for admission was cancer treatment (19.6%), followed by infections (18.7%) and digestive tract symptoms (18.7%). Overall, 77.5% (83/107) of the patients were malnourished at admission according to the GLIM criteria, while 52.3% (56/107) were sarcopenic. Nosocomial infections (NI) were significantly more frequent in malnourished (52.1%; 25/48) and severely malnourished (42.1%; 8/19) patients, compared with well-nourished patients without malnutrition (25%; 10/40; p=0.035). The mean length of hospital stay was 13.9 days, significantly longer in patients with an NI compared to those without infections (18.6 vs. 10.8 days, p<0.024). Conclusion. This study evidenced the need to implement a routine protocol for the nutritional assessment and support of cancer patients at risk of malnutrition and sarcopenia to reduce the risk of NI during their hospital stay. |
| format | Article |
| id | doaj-art-3e5a4a9aa9b149efb3202ec2a489608e |
| institution | Kabale University |
| issn | 2090-0732 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Nutrition and Metabolism |
| spelling | doaj-art-3e5a4a9aa9b149efb3202ec2a489608e2025-02-03T01:23:38ZengWileyJournal of Nutrition and Metabolism2090-07322022-01-01202210.1155/2022/5232480Relation of Malnutrition and Nosocomical Infections in Cancer Patients in Hospital: An Observational StudyBianca Tabita Muresan0Martín Núñez‐Abad1Ana Artero2Jaime Rios Rios3Alberto Jacobo Cunquero-Tomás4Vega Iranzo5Javier Garrido6Ana Jiménez-Portilla7Carlos Camps Herrero8Carlos J. Sánchez Juan9Servicio de Endocrinología y NutriciónServicio de Oncología MédicaServicio de Endocrinología y NutriciónServicio de Urgencias HospitalariasFundación Hospital General Universitario de ValenciaServicio de Oncología MédicaServicio de Oncología MédicaServicio de Endocrinología y NutriciónCentro de Investigación Biomédica en Red Cáncer CIBERONCServicio de Endocrinología y NutriciónAim. To investigate the relation between malnutrition and nosocomial infections (NI) in hospitalized cancer patients. Methods. This observational, cross-sectional, noninterventional, descriptive study was conducted in a 500-bed university hospital in Valencia (Spain). Adult cancer patients admitted to the oncology ward were consecutively enrolled regardless of their nutritional status between November 2019 and March 2020. Patients were nutritionally assessed 24 to 48 hours after admission. Body weight, height and BMI, body composition through measurement of bioelectrical impedance analysis (BIA), and muscle strength and functionality using hand grip strength (HGS) were prospectively collected. The diagnosis of malnutrition and sarcopenia was assessed using the Global Leadership Initiative on Malnutrition (GLIM) criteria and the European Working Group on Sarcopenia in Older People (EWGSOP) criteria, respectively. Patients were followed up during their hospital stay or outpatient oncology visits to identify possible NI. Results. A total of 107 patients were included in this study (mean age 66 years; 66.4% were men). The most frequent reason for admission was cancer treatment (19.6%), followed by infections (18.7%) and digestive tract symptoms (18.7%). Overall, 77.5% (83/107) of the patients were malnourished at admission according to the GLIM criteria, while 52.3% (56/107) were sarcopenic. Nosocomial infections (NI) were significantly more frequent in malnourished (52.1%; 25/48) and severely malnourished (42.1%; 8/19) patients, compared with well-nourished patients without malnutrition (25%; 10/40; p=0.035). The mean length of hospital stay was 13.9 days, significantly longer in patients with an NI compared to those without infections (18.6 vs. 10.8 days, p<0.024). Conclusion. This study evidenced the need to implement a routine protocol for the nutritional assessment and support of cancer patients at risk of malnutrition and sarcopenia to reduce the risk of NI during their hospital stay.http://dx.doi.org/10.1155/2022/5232480 |
| spellingShingle | Bianca Tabita Muresan Martín Núñez‐Abad Ana Artero Jaime Rios Rios Alberto Jacobo Cunquero-Tomás Vega Iranzo Javier Garrido Ana Jiménez-Portilla Carlos Camps Herrero Carlos J. Sánchez Juan Relation of Malnutrition and Nosocomical Infections in Cancer Patients in Hospital: An Observational Study Journal of Nutrition and Metabolism |
| title | Relation of Malnutrition and Nosocomical Infections in Cancer Patients in Hospital: An Observational Study |
| title_full | Relation of Malnutrition and Nosocomical Infections in Cancer Patients in Hospital: An Observational Study |
| title_fullStr | Relation of Malnutrition and Nosocomical Infections in Cancer Patients in Hospital: An Observational Study |
| title_full_unstemmed | Relation of Malnutrition and Nosocomical Infections in Cancer Patients in Hospital: An Observational Study |
| title_short | Relation of Malnutrition and Nosocomical Infections in Cancer Patients in Hospital: An Observational Study |
| title_sort | relation of malnutrition and nosocomical infections in cancer patients in hospital an observational study |
| url | http://dx.doi.org/10.1155/2022/5232480 |
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