Impact of Preoperative Anemia on Perioperative Outcomes in Patients Undergoing Elective Colorectal Surgery
Aim. To evaluate the impact of preoperative anemia (POA) on perioperative outcomes in patients undergoing elective surgery for colorectal cancer (CRC). Methods. A total of 326 CRC patients were enrolled. POA was defined as a hemoglobin (Hb) concentration ≤ 12 g/dl. Univariable and multivariable anal...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2018/2417028 |
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| author | Liu Liu Lin Liu Li-Chuang Liang Zhi-qiang Zhu Xiao Wan Heng-bing Dai Qiang Huang |
| author_facet | Liu Liu Lin Liu Li-Chuang Liang Zhi-qiang Zhu Xiao Wan Heng-bing Dai Qiang Huang |
| author_sort | Liu Liu |
| collection | DOAJ |
| description | Aim. To evaluate the impact of preoperative anemia (POA) on perioperative outcomes in patients undergoing elective surgery for colorectal cancer (CRC). Methods. A total of 326 CRC patients were enrolled. POA was defined as a hemoglobin (Hb) concentration ≤ 12 g/dl. Univariable and multivariable analyses were performed to assess the impact of POA on the risks of postoperative complications like surgical site infection (SSI). Results. Patients with colon cancer presented higher rate of POA than patients with rectal cancer (60% versus 40% for colon cancer versus rectal cancer). In addition, female patients and patients with large tumor mass (>4 cm) had a higher rate of POA than male patients and patients with small tumor (≤4 cm), respectively. Upon univariable analysis, CRC patients with POA had a higher rate of incisional SSI than patients without POA (12% versus 6%, P=0.04). However, POA was not associated with other postoperative complications, like anastomotic leak, organ space SSI, and bleeding. Upon multivariable analysis, POA and stoma formation were identified as two independent risk factors for incisional SSI (OR (95%CI): 2.44 (1.09–5.49) for POA versus no POA and 2.64 (1.20–5.81) for stoma formation versus no stoma formation). Conclusions. POA was an independent risk factor for incisional surgical site infection after colorectal resection for CRC, and correcting POA should be considered before elective surgery. |
| format | Article |
| id | doaj-art-3e318299161f44b48bf9af7c5cdeffc0 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-3e318299161f44b48bf9af7c5cdeffc02025-02-03T01:32:36ZengWileyGastroenterology Research and Practice1687-61211687-630X2018-01-01201810.1155/2018/24170282417028Impact of Preoperative Anemia on Perioperative Outcomes in Patients Undergoing Elective Colorectal SurgeryLiu Liu0Lin Liu1Li-Chuang Liang2Zhi-qiang Zhu3Xiao Wan4Heng-bing Dai5Qiang Huang6Department of General Surgery, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui Province 230001, ChinaDepartment of Anesthesiology, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui Province, ChinaDepartment of General Surgery, Anhui Provincial Hospital Affiliated to the Anhui Medical University, Hefei, Anhui Province 230001, ChinaDepartment of General Surgery, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui Province 230001, ChinaDepartment of General Surgery, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui Province 230001, ChinaDepartment of General Surgery, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui Province 230001, ChinaDepartment of General Surgery, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui Province 230001, ChinaAim. To evaluate the impact of preoperative anemia (POA) on perioperative outcomes in patients undergoing elective surgery for colorectal cancer (CRC). Methods. A total of 326 CRC patients were enrolled. POA was defined as a hemoglobin (Hb) concentration ≤ 12 g/dl. Univariable and multivariable analyses were performed to assess the impact of POA on the risks of postoperative complications like surgical site infection (SSI). Results. Patients with colon cancer presented higher rate of POA than patients with rectal cancer (60% versus 40% for colon cancer versus rectal cancer). In addition, female patients and patients with large tumor mass (>4 cm) had a higher rate of POA than male patients and patients with small tumor (≤4 cm), respectively. Upon univariable analysis, CRC patients with POA had a higher rate of incisional SSI than patients without POA (12% versus 6%, P=0.04). However, POA was not associated with other postoperative complications, like anastomotic leak, organ space SSI, and bleeding. Upon multivariable analysis, POA and stoma formation were identified as two independent risk factors for incisional SSI (OR (95%CI): 2.44 (1.09–5.49) for POA versus no POA and 2.64 (1.20–5.81) for stoma formation versus no stoma formation). Conclusions. POA was an independent risk factor for incisional surgical site infection after colorectal resection for CRC, and correcting POA should be considered before elective surgery.http://dx.doi.org/10.1155/2018/2417028 |
| spellingShingle | Liu Liu Lin Liu Li-Chuang Liang Zhi-qiang Zhu Xiao Wan Heng-bing Dai Qiang Huang Impact of Preoperative Anemia on Perioperative Outcomes in Patients Undergoing Elective Colorectal Surgery Gastroenterology Research and Practice |
| title | Impact of Preoperative Anemia on Perioperative Outcomes in Patients Undergoing Elective Colorectal Surgery |
| title_full | Impact of Preoperative Anemia on Perioperative Outcomes in Patients Undergoing Elective Colorectal Surgery |
| title_fullStr | Impact of Preoperative Anemia on Perioperative Outcomes in Patients Undergoing Elective Colorectal Surgery |
| title_full_unstemmed | Impact of Preoperative Anemia on Perioperative Outcomes in Patients Undergoing Elective Colorectal Surgery |
| title_short | Impact of Preoperative Anemia on Perioperative Outcomes in Patients Undergoing Elective Colorectal Surgery |
| title_sort | impact of preoperative anemia on perioperative outcomes in patients undergoing elective colorectal surgery |
| url | http://dx.doi.org/10.1155/2018/2417028 |
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