Hospital Admission Patterns in Children with CAH: Admission Rates and Adrenal Crises Decline with Age

Objective. To examine patterns of hospitalisation for acute medical conditions in children with congenital adrenal hyperplasia (CAH). Design. A retrospective study of hospitalisation using administrative data. Setting. All hospitals in NSW, Australia. Patients. All patients admitted with CAH and a r...

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Main Authors: R. Louise Rushworth, Henrik Falhammar, Craig F. Munns, Ann M. Maguire, David J. Torpy
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2016/5748264
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author R. Louise Rushworth
Henrik Falhammar
Craig F. Munns
Ann M. Maguire
David J. Torpy
author_facet R. Louise Rushworth
Henrik Falhammar
Craig F. Munns
Ann M. Maguire
David J. Torpy
author_sort R. Louise Rushworth
collection DOAJ
description Objective. To examine patterns of hospitalisation for acute medical conditions in children with congenital adrenal hyperplasia (CAH). Design. A retrospective study of hospitalisation using administrative data. Setting. All hospitals in NSW, Australia. Patients. All patients admitted with CAH and a random sample of admissions in patients aged 0 to 18 years without adrenal insufficiency (AI). Main Outcome Measures. Admissions and comorbidities by age and sex. Results. Of 573 admissions for medical problems in CAH children, 286 (49.9%) were in males, and 236 (41.2%) had a principal diagnosis of CAH or had an adrenal crisis (AC). 37 (6.5%) ACs were recorded. An infection was found in 43.5% (n=249) of the CAH patient admissions and 51.7% (n=1613) of the non-AI group, p<0.001. Children aged up to one year had the highest number of admissions (n=149) and six ACs (four in males). There were 21 ACs recorded for children aged 1–5 years. Older CAH children had fewer admissions and fewer ACs. No in-hospital deaths were recorded. Conclusions. Admission for medical problems in CAH children declines with age. An AC was recorded in 6.5% of the admissions, with the majority of ACs occurring in the 1 to 5 years age group and there were no deaths.
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spelling doaj-art-3e2b8bd94c7e461e982a74af8093bccc2025-08-20T03:55:41ZengWileyInternational Journal of Endocrinology1687-83371687-83452016-01-01201610.1155/2016/57482645748264Hospital Admission Patterns in Children with CAH: Admission Rates and Adrenal Crises Decline with AgeR. Louise Rushworth0Henrik Falhammar1Craig F. Munns2Ann M. Maguire3David J. Torpy4School of Medicine, Sydney, The University of Notre Dame, Australia, 160 Oxford Street, Darlinghurst, NSW 2010, AustraliaDepartment of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, 171 76 Stockholm, SwedenEndocrinology and Diabetes, The Children’s Hospital Westmead, Hawkesbury Road, Westmead, NSW 2145, AustraliaEndocrinology and Diabetes, The Children’s Hospital Westmead, Hawkesbury Road, Westmead, NSW 2145, AustraliaEndocrine and Metabolic Unit, Royal Adelaide Hospital and University of Adelaide, North Terrace, Adelaide, SA 5000, AustraliaObjective. To examine patterns of hospitalisation for acute medical conditions in children with congenital adrenal hyperplasia (CAH). Design. A retrospective study of hospitalisation using administrative data. Setting. All hospitals in NSW, Australia. Patients. All patients admitted with CAH and a random sample of admissions in patients aged 0 to 18 years without adrenal insufficiency (AI). Main Outcome Measures. Admissions and comorbidities by age and sex. Results. Of 573 admissions for medical problems in CAH children, 286 (49.9%) were in males, and 236 (41.2%) had a principal diagnosis of CAH or had an adrenal crisis (AC). 37 (6.5%) ACs were recorded. An infection was found in 43.5% (n=249) of the CAH patient admissions and 51.7% (n=1613) of the non-AI group, p<0.001. Children aged up to one year had the highest number of admissions (n=149) and six ACs (four in males). There were 21 ACs recorded for children aged 1–5 years. Older CAH children had fewer admissions and fewer ACs. No in-hospital deaths were recorded. Conclusions. Admission for medical problems in CAH children declines with age. An AC was recorded in 6.5% of the admissions, with the majority of ACs occurring in the 1 to 5 years age group and there were no deaths.http://dx.doi.org/10.1155/2016/5748264
spellingShingle R. Louise Rushworth
Henrik Falhammar
Craig F. Munns
Ann M. Maguire
David J. Torpy
Hospital Admission Patterns in Children with CAH: Admission Rates and Adrenal Crises Decline with Age
International Journal of Endocrinology
title Hospital Admission Patterns in Children with CAH: Admission Rates and Adrenal Crises Decline with Age
title_full Hospital Admission Patterns in Children with CAH: Admission Rates and Adrenal Crises Decline with Age
title_fullStr Hospital Admission Patterns in Children with CAH: Admission Rates and Adrenal Crises Decline with Age
title_full_unstemmed Hospital Admission Patterns in Children with CAH: Admission Rates and Adrenal Crises Decline with Age
title_short Hospital Admission Patterns in Children with CAH: Admission Rates and Adrenal Crises Decline with Age
title_sort hospital admission patterns in children with cah admission rates and adrenal crises decline with age
url http://dx.doi.org/10.1155/2016/5748264
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