Radiofrequency Ablation in the Management of Advanced Stage Thymomas: A Case Report on a Novel Multidisciplinary Therapeutic Approach

We describe in this report a case of successful radiofrequency ablation of an unresectable stage III-type B3 thymoma, and we discuss the role of this novel approach in the management of patients with advanced stage thymoma. The patient, a 59-year-old Caucasian male underwent neoadjuvant chemotherapy...

Full description

Saved in:
Bibliographic Details
Main Authors: Panagiotis Paliogiannis, Carlo Pala, Renato Versace, Claudio Pusceddu
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/2014/697480
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832552115258523648
author Panagiotis Paliogiannis
Carlo Pala
Renato Versace
Claudio Pusceddu
author_facet Panagiotis Paliogiannis
Carlo Pala
Renato Versace
Claudio Pusceddu
author_sort Panagiotis Paliogiannis
collection DOAJ
description We describe in this report a case of successful radiofrequency ablation of an unresectable stage III-type B3 thymoma, and we discuss the role of this novel approach in the management of patients with advanced stage thymoma. The patient, a 59-year-old Caucasian male underwent neoadjuvant chemotherapy with only a slight reduction of the mass. Subsequently, an explorative sternotomy and debulking were performed; before closing the thorax, radiofrequency ablation of the residual tumor was carried out and a partial necrosis of the mass was achieved. A further percutaneous radiofrequency ablation was performed subsequently, obtaining complete necrosis of the lesion. Successively, the patient underwent adjuvant radiotherapy. As a result of this multidisciplinary treatment, complete and stable response was obtained. It is hard to say which of the single treatments had the major impact on cure; nevertheless, the results obtained suggest that radiofrequency ablation must be taken into account for the treatment of advanced stage thymomas, and its effectiveness must be further assessed in future studies.
format Article
id doaj-art-3e2132f116894388a415b7821f231276
institution Kabale University
issn 2090-6862
2090-6870
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Case Reports in Radiology
spelling doaj-art-3e2132f116894388a415b7821f2312762025-02-03T05:59:30ZengWileyCase Reports in Radiology2090-68622090-68702014-01-01201410.1155/2014/697480697480Radiofrequency Ablation in the Management of Advanced Stage Thymomas: A Case Report on a Novel Multidisciplinary Therapeutic ApproachPanagiotis Paliogiannis0Carlo Pala1Renato Versace2Claudio Pusceddu3Surgical Pathology, Department of Surgical, Microsurgical and Medical Sciences, University of Sassari, Viale San Pietro 43B, 07100 Sassari, ItalySurgical Pathology, Department of Surgical, Microsurgical and Medical Sciences, University of Sassari, Viale San Pietro 43B, 07100 Sassari, ItalyDepartment of Thoracic Surgery, Oncological Hospital of Cagliari, Via E. Jenner 1, 09100 Cagliari, ItalyDepartment of Radio-Oncology, Oncological Hospital of Cagliari, Via E. Jenner 1, 09100 Cagliari, ItalyWe describe in this report a case of successful radiofrequency ablation of an unresectable stage III-type B3 thymoma, and we discuss the role of this novel approach in the management of patients with advanced stage thymoma. The patient, a 59-year-old Caucasian male underwent neoadjuvant chemotherapy with only a slight reduction of the mass. Subsequently, an explorative sternotomy and debulking were performed; before closing the thorax, radiofrequency ablation of the residual tumor was carried out and a partial necrosis of the mass was achieved. A further percutaneous radiofrequency ablation was performed subsequently, obtaining complete necrosis of the lesion. Successively, the patient underwent adjuvant radiotherapy. As a result of this multidisciplinary treatment, complete and stable response was obtained. It is hard to say which of the single treatments had the major impact on cure; nevertheless, the results obtained suggest that radiofrequency ablation must be taken into account for the treatment of advanced stage thymomas, and its effectiveness must be further assessed in future studies.http://dx.doi.org/10.1155/2014/697480
spellingShingle Panagiotis Paliogiannis
Carlo Pala
Renato Versace
Claudio Pusceddu
Radiofrequency Ablation in the Management of Advanced Stage Thymomas: A Case Report on a Novel Multidisciplinary Therapeutic Approach
Case Reports in Radiology
title Radiofrequency Ablation in the Management of Advanced Stage Thymomas: A Case Report on a Novel Multidisciplinary Therapeutic Approach
title_full Radiofrequency Ablation in the Management of Advanced Stage Thymomas: A Case Report on a Novel Multidisciplinary Therapeutic Approach
title_fullStr Radiofrequency Ablation in the Management of Advanced Stage Thymomas: A Case Report on a Novel Multidisciplinary Therapeutic Approach
title_full_unstemmed Radiofrequency Ablation in the Management of Advanced Stage Thymomas: A Case Report on a Novel Multidisciplinary Therapeutic Approach
title_short Radiofrequency Ablation in the Management of Advanced Stage Thymomas: A Case Report on a Novel Multidisciplinary Therapeutic Approach
title_sort radiofrequency ablation in the management of advanced stage thymomas a case report on a novel multidisciplinary therapeutic approach
url http://dx.doi.org/10.1155/2014/697480
work_keys_str_mv AT panagiotispaliogiannis radiofrequencyablationinthemanagementofadvancedstagethymomasacasereportonanovelmultidisciplinarytherapeuticapproach
AT carlopala radiofrequencyablationinthemanagementofadvancedstagethymomasacasereportonanovelmultidisciplinarytherapeuticapproach
AT renatoversace radiofrequencyablationinthemanagementofadvancedstagethymomasacasereportonanovelmultidisciplinarytherapeuticapproach
AT claudiopusceddu radiofrequencyablationinthemanagementofadvancedstagethymomasacasereportonanovelmultidisciplinarytherapeuticapproach