Relative expression orderings based prediction of treatment response to Anti-PD-1 immunotherapy in advanced melanoma

Relative expression orderings based prediction of treatment response to Anti-PD-1 immunotherapy in advanced melanoma

Abstract Programmed cell death protein 1 (PD-1) plays a critical role in immune tolerance and evasion within the tumor microenvironment, and anti-PD-1 immunotherapy has shown efficacy in treating advanced melanoma. However, response rates vary significantly among patients, necessitating the identifi...

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Bibliographic Details
Main Authors: Yaru Gao, Yue Huo, Lingli Wang, Jiayi Ruan, Lanzhen Chen, Hongdong Li, Guini Hong
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Melanoma
anti-PD-1 immunotherapy
Biomarker
REOs
Online Access:https://doi.org/10.1038/s41598-025-94931-0
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