Biopsy-Proven Acute Tubular Necrosis due to Vancomycin Toxicity
Vancomycin (VAN) has been associated with acute kidney injury (AKI) since it has been put into clinical use in the 1950's. Early reports of AKI were likely linked to the impurities of the VAN preparation. With the advent of the more purified forms of VAN, the incidence of AKI related to VAN wer...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
|
| Series: | International Journal of Nephrology |
| Online Access: | http://dx.doi.org/10.4061/2011/436856 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832557087181242368 |
|---|---|
| author | Farheen Shah-Khan Marc H. Scheetz Cybele Ghossein |
| author_facet | Farheen Shah-Khan Marc H. Scheetz Cybele Ghossein |
| author_sort | Farheen Shah-Khan |
| collection | DOAJ |
| description | Vancomycin (VAN) has been associated with acute kidney injury (AKI) since it has been put into clinical use in the 1950's. Early reports of AKI were likely linked to the impurities of the VAN preparation. With the advent of the more purified forms of VAN, the incidence of AKI related to VAN were limited to acute interstitial nephritis (AIN) or as a potentiating agent to other nephrotoxins such as Aminoglycosides. VAN as the sole etiologic factor for nephrotoxic acute tubular necrosis (ATN) has not been described. Here, we report a case of biopsy-proven ATN resulting from VAN. |
| format | Article |
| id | doaj-art-3e07bd1475474f009c297113f3a4cc93 |
| institution | Kabale University |
| issn | 2090-214X 2090-2158 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Nephrology |
| spelling | doaj-art-3e07bd1475474f009c297113f3a4cc932025-02-03T05:43:41ZengWileyInternational Journal of Nephrology2090-214X2090-21582011-01-01201110.4061/2011/436856436856Biopsy-Proven Acute Tubular Necrosis due to Vancomycin ToxicityFarheen Shah-Khan0Marc H. Scheetz1Cybele Ghossein2Division of Nephrology, Northwestern Memorial Hospital, Chicago, IL 60611, USADepartment of Pharmacy Practice, College of Pharmacy, Midwestern University Chicago, Downers Grove, IL 60515, USADivision of Nephrology, Northwestern Memorial Hospital, Chicago, IL 60611, USAVancomycin (VAN) has been associated with acute kidney injury (AKI) since it has been put into clinical use in the 1950's. Early reports of AKI were likely linked to the impurities of the VAN preparation. With the advent of the more purified forms of VAN, the incidence of AKI related to VAN were limited to acute interstitial nephritis (AIN) or as a potentiating agent to other nephrotoxins such as Aminoglycosides. VAN as the sole etiologic factor for nephrotoxic acute tubular necrosis (ATN) has not been described. Here, we report a case of biopsy-proven ATN resulting from VAN.http://dx.doi.org/10.4061/2011/436856 |
| spellingShingle | Farheen Shah-Khan Marc H. Scheetz Cybele Ghossein Biopsy-Proven Acute Tubular Necrosis due to Vancomycin Toxicity International Journal of Nephrology |
| title | Biopsy-Proven Acute Tubular Necrosis due to Vancomycin Toxicity |
| title_full | Biopsy-Proven Acute Tubular Necrosis due to Vancomycin Toxicity |
| title_fullStr | Biopsy-Proven Acute Tubular Necrosis due to Vancomycin Toxicity |
| title_full_unstemmed | Biopsy-Proven Acute Tubular Necrosis due to Vancomycin Toxicity |
| title_short | Biopsy-Proven Acute Tubular Necrosis due to Vancomycin Toxicity |
| title_sort | biopsy proven acute tubular necrosis due to vancomycin toxicity |
| url | http://dx.doi.org/10.4061/2011/436856 |
| work_keys_str_mv | AT farheenshahkhan biopsyprovenacutetubularnecrosisduetovancomycintoxicity AT marchscheetz biopsyprovenacutetubularnecrosisduetovancomycintoxicity AT cybeleghossein biopsyprovenacutetubularnecrosisduetovancomycintoxicity |