The Hepatitis C Genotype 1 Paradox: Cost per Treatment Is Increasing, but Cost per Cure Is Decreasing

Significant attention has been focused on the perceived increase in the cost of antiviral treatment for hepatitis C genotype 1 infection since the approval of the first direct-acting antiviral agents in 2011. Using Canadian list prices, the present analysis points out a paradox: while the cost per a...

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Main Author: Stephen D Shafran
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2015/216395
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author Stephen D Shafran
author_facet Stephen D Shafran
author_sort Stephen D Shafran
collection DOAJ
description Significant attention has been focused on the perceived increase in the cost of antiviral treatment for hepatitis C genotype 1 infection since the approval of the first direct-acting antiviral agents in 2011. Using Canadian list prices, the present analysis points out a paradox: while the cost per antiviral regimen is increasing, the cost per cure is decreasing, especially with interferon-free therapy. In a publicly funded health care system, the lowest cost per cure is a more valuable measure of value for public money than the cost per regimen.
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spelling doaj-art-3e00898b14f14ec0b40154c97005c15f2025-02-03T01:31:32ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972015-01-01291464810.1155/2015/216395The Hepatitis C Genotype 1 Paradox: Cost per Treatment Is Increasing, but Cost per Cure Is DecreasingStephen D Shafran0Division of Infectious Diseases, Department of Medicine, University of Alberta, Edmonton, Alberta, CanadaSignificant attention has been focused on the perceived increase in the cost of antiviral treatment for hepatitis C genotype 1 infection since the approval of the first direct-acting antiviral agents in 2011. Using Canadian list prices, the present analysis points out a paradox: while the cost per antiviral regimen is increasing, the cost per cure is decreasing, especially with interferon-free therapy. In a publicly funded health care system, the lowest cost per cure is a more valuable measure of value for public money than the cost per regimen.http://dx.doi.org/10.1155/2015/216395
spellingShingle Stephen D Shafran
The Hepatitis C Genotype 1 Paradox: Cost per Treatment Is Increasing, but Cost per Cure Is Decreasing
Canadian Journal of Gastroenterology and Hepatology
title The Hepatitis C Genotype 1 Paradox: Cost per Treatment Is Increasing, but Cost per Cure Is Decreasing
title_full The Hepatitis C Genotype 1 Paradox: Cost per Treatment Is Increasing, but Cost per Cure Is Decreasing
title_fullStr The Hepatitis C Genotype 1 Paradox: Cost per Treatment Is Increasing, but Cost per Cure Is Decreasing
title_full_unstemmed The Hepatitis C Genotype 1 Paradox: Cost per Treatment Is Increasing, but Cost per Cure Is Decreasing
title_short The Hepatitis C Genotype 1 Paradox: Cost per Treatment Is Increasing, but Cost per Cure Is Decreasing
title_sort hepatitis c genotype 1 paradox cost per treatment is increasing but cost per cure is decreasing
url http://dx.doi.org/10.1155/2015/216395
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AT stephendshafran hepatitiscgenotype1paradoxcostpertreatmentisincreasingbutcostpercureisdecreasing