The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats
In the present study, we assessed the treatment effects of PBDE-209 administration on the immune function in rats during pregnancy and lactation. We harvested the blood and organs for flow cytometry, viability assay, enzyme-linked immunosorbent assay, and histological evaluation. The results of this...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2012/692467 |
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| _version_ | 1832555416604639232 |
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| author | Xianbao Liu Hong Zhan Xu Zeng Chunfang Zhang Dunjin Chen |
| author_facet | Xianbao Liu Hong Zhan Xu Zeng Chunfang Zhang Dunjin Chen |
| author_sort | Xianbao Liu |
| collection | DOAJ |
| description | In the present study, we assessed the treatment effects of PBDE-209 administration on the immune function in rats during pregnancy and lactation. We harvested the blood and organs for flow cytometry, viability assay, enzyme-linked immunosorbent assay, and histological evaluation. The results of this study were the PBDE-209 exposure during pregnancy and lactation impairs immune function in rats. The results may contribute to understanding the mechanism of PBDE-209 in immune function. |
| format | Article |
| id | doaj-art-3dfa91fba9cf4bf4b9dc44f9cf0dad86 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-3dfa91fba9cf4bf4b9dc44f9cf0dad862025-02-03T05:48:15ZengWileyMediators of Inflammation0962-93511466-18612012-01-01201210.1155/2012/692467692467The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in RatsXianbao Liu0Hong Zhan1Xu Zeng2Chunfang Zhang3Dunjin Chen4The Third Affiliated Hospital of Guangzhou Medical College, The Medical Center for Critical Pregnant Women in Guangzhou, Duobao Road, No. 63, Guangzhou 510150, ChinaThe Third Affiliated Hospital of Guangzhou Medical College, The Medical Center for Critical Pregnant Women in Guangzhou, Duobao Road, No. 63, Guangzhou 510150, ChinaDepartment of Pathology, Detroit Medical Center, Harper Hospital, School of Medicine, Wayne State University, 3990 John R, Detroit, MI 48201, USAThe Third Affiliated Hospital of Guangzhou Medical College, The Medical Center for Critical Pregnant Women in Guangzhou, Duobao Road, No. 63, Guangzhou 510150, ChinaThe Third Affiliated Hospital of Guangzhou Medical College, The Medical Center for Critical Pregnant Women in Guangzhou, Duobao Road, No. 63, Guangzhou 510150, ChinaIn the present study, we assessed the treatment effects of PBDE-209 administration on the immune function in rats during pregnancy and lactation. We harvested the blood and organs for flow cytometry, viability assay, enzyme-linked immunosorbent assay, and histological evaluation. The results of this study were the PBDE-209 exposure during pregnancy and lactation impairs immune function in rats. The results may contribute to understanding the mechanism of PBDE-209 in immune function.http://dx.doi.org/10.1155/2012/692467 |
| spellingShingle | Xianbao Liu Hong Zhan Xu Zeng Chunfang Zhang Dunjin Chen The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats Mediators of Inflammation |
| title | The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats |
| title_full | The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats |
| title_fullStr | The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats |
| title_full_unstemmed | The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats |
| title_short | The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats |
| title_sort | pbde 209 exposure during pregnancy and lactation impairs immune function in rats |
| url | http://dx.doi.org/10.1155/2012/692467 |
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