Inspiratroy Capacity and Exercise Tolerance in Chronic Obstructive Pulmonary Disease

During the past half-century, many studies have investigated the correlation of exercise tolerance to routine lung function in patients with obstructive pulmonary disease. In virtually all of these studies, the degree of airway obstruction was assessed in terms of forced expiratory volume in 1 s...

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Main Author: Joseph Milic-Emili
Format: Article
Language:English
Published: Wiley 2000-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2000/745686
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author Joseph Milic-Emili
author_facet Joseph Milic-Emili
author_sort Joseph Milic-Emili
collection DOAJ
description During the past half-century, many studies have investigated the correlation of exercise tolerance to routine lung function in patients with obstructive pulmonary disease. In virtually all of these studies, the degree of airway obstruction was assessed in terms of forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC). Because in most studies only a weak correlation was found between exercise tolerance and degree of airway obstruction, it has been concluded that factors other than lung function impairment (eg, deconditioning and peripheral muscle dysfunction) play a predominant role in limiting exercise capacity in patients with chronic airway obstruction. Recent work, however, suggests that in patients with chronic obstructive pulmonary disease, the inspiratory capacity is a more powerful predictor of exercise tolerance than FEV1 and FVC.
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spelling doaj-art-3dfa35dde04f418db9264b20bbde9d0b2025-02-03T06:05:37ZengWileyCanadian Respiratory Journal1198-22412000-01-017328228510.1155/2000/745686Inspiratroy Capacity and Exercise Tolerance in Chronic Obstructive Pulmonary DiseaseJoseph Milic-EmiliDuring the past half-century, many studies have investigated the correlation of exercise tolerance to routine lung function in patients with obstructive pulmonary disease. In virtually all of these studies, the degree of airway obstruction was assessed in terms of forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC). Because in most studies only a weak correlation was found between exercise tolerance and degree of airway obstruction, it has been concluded that factors other than lung function impairment (eg, deconditioning and peripheral muscle dysfunction) play a predominant role in limiting exercise capacity in patients with chronic airway obstruction. Recent work, however, suggests that in patients with chronic obstructive pulmonary disease, the inspiratory capacity is a more powerful predictor of exercise tolerance than FEV1 and FVC.http://dx.doi.org/10.1155/2000/745686
spellingShingle Joseph Milic-Emili
Inspiratroy Capacity and Exercise Tolerance in Chronic Obstructive Pulmonary Disease
Canadian Respiratory Journal
title Inspiratroy Capacity and Exercise Tolerance in Chronic Obstructive Pulmonary Disease
title_full Inspiratroy Capacity and Exercise Tolerance in Chronic Obstructive Pulmonary Disease
title_fullStr Inspiratroy Capacity and Exercise Tolerance in Chronic Obstructive Pulmonary Disease
title_full_unstemmed Inspiratroy Capacity and Exercise Tolerance in Chronic Obstructive Pulmonary Disease
title_short Inspiratroy Capacity and Exercise Tolerance in Chronic Obstructive Pulmonary Disease
title_sort inspiratroy capacity and exercise tolerance in chronic obstructive pulmonary disease
url http://dx.doi.org/10.1155/2000/745686
work_keys_str_mv AT josephmilicemili inspiratroycapacityandexercisetoleranceinchronicobstructivepulmonarydisease