Activation of PPAR𝛾 by Rosiglitazone Does Not Negatively Impact Male Sex Steroid Hormones in Diabetic Rats
Peroxisome proliferator-activated receptor gamma (PPAR𝛾) activation decreased serum testosterone (T) in women with hyperthecosis and/or polycystic ovary syndrome and reduced the conversion of androgens to estradiol (E2) in female rats. This implies modulation of female sex steroid hormones by PPAR𝛾....
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Main Authors: | Mahmoud Mansour, Elaine Coleman, John Dennis, Benson Akingbemi, Dean Schwartz, Tim Braden, Robert Judd, Eric Plaisance, Laura Ken Stewart, Edward Morrison |
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Format: | Article |
Language: | English |
Published: |
Wiley
2009-01-01
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Series: | PPAR Research |
Online Access: | http://dx.doi.org/10.1155/2009/101857 |
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