Surface-Enhanced Oxidation and Determination of Isothipendyl Hydrochloride at an Electrochemical Sensing Film Constructed by Multiwalled Carbon Nanotubes
The electrochemical behavior of isothipendyl hydrochloride (IPH) was investigated at bare and multiwalled-carbon-nanotube modified glassy carbon electrode (MWCNT-GCE). IPH (55 μM) showed two oxidation peaks in Britton-Robinson (BR) buffer of pH 7.0. The oxidation process of IPH was observed to be ir...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Electrochemistry |
| Online Access: | http://dx.doi.org/10.1155/2012/875631 |
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| author | S. N. Prashanth Shankara S. Kalanur Nagappa L. Teradal J. Seetharamappa |
| author_facet | S. N. Prashanth Shankara S. Kalanur Nagappa L. Teradal J. Seetharamappa |
| author_sort | S. N. Prashanth |
| collection | DOAJ |
| description | The electrochemical behavior of isothipendyl hydrochloride (IPH) was investigated at bare and multiwalled-carbon-nanotube modified glassy carbon electrode (MWCNT-GCE). IPH (55 μM) showed two oxidation peaks in Britton-Robinson (BR) buffer of pH 7.0. The oxidation process of IPH was observed to be irreversible over the pH range of 2.5–9.0. The influence of pH, scan rate, and concentration of the drug on anodic peak was studied. A differential pulse voltammetric method with good precision and accuracy was developed for the determination of IPH in pure and biological fluids. The peak current was found to be linearly dependent on the concentration of IPH in the range of 1.25–55 μM. The values of limit of detection and limit of quantification were noticed to be 0.284 and 0.949 μM, respectively. |
| format | Article |
| id | doaj-art-3df08e5ff8dd41d0a2cb6c3d45fce04d |
| institution | Kabale University |
| issn | 2090-3529 2090-3537 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
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| series | International Journal of Electrochemistry |
| spelling | doaj-art-3df08e5ff8dd41d0a2cb6c3d45fce04d2025-02-03T05:44:23ZengWileyInternational Journal of Electrochemistry2090-35292090-35372012-01-01201210.1155/2012/875631875631Surface-Enhanced Oxidation and Determination of Isothipendyl Hydrochloride at an Electrochemical Sensing Film Constructed by Multiwalled Carbon NanotubesS. N. Prashanth0Shankara S. Kalanur1Nagappa L. Teradal2J. Seetharamappa3Department of Chemistry, Karnatak University, Dharwad 580 003, IndiaDepartment of Chemistry, Karnatak University, Dharwad 580 003, IndiaDepartment of Chemistry, Karnatak University, Dharwad 580 003, IndiaDepartment of Chemistry, Karnatak University, Dharwad 580 003, IndiaThe electrochemical behavior of isothipendyl hydrochloride (IPH) was investigated at bare and multiwalled-carbon-nanotube modified glassy carbon electrode (MWCNT-GCE). IPH (55 μM) showed two oxidation peaks in Britton-Robinson (BR) buffer of pH 7.0. The oxidation process of IPH was observed to be irreversible over the pH range of 2.5–9.0. The influence of pH, scan rate, and concentration of the drug on anodic peak was studied. A differential pulse voltammetric method with good precision and accuracy was developed for the determination of IPH in pure and biological fluids. The peak current was found to be linearly dependent on the concentration of IPH in the range of 1.25–55 μM. The values of limit of detection and limit of quantification were noticed to be 0.284 and 0.949 μM, respectively.http://dx.doi.org/10.1155/2012/875631 |
| spellingShingle | S. N. Prashanth Shankara S. Kalanur Nagappa L. Teradal J. Seetharamappa Surface-Enhanced Oxidation and Determination of Isothipendyl Hydrochloride at an Electrochemical Sensing Film Constructed by Multiwalled Carbon Nanotubes International Journal of Electrochemistry |
| title | Surface-Enhanced Oxidation and Determination of Isothipendyl Hydrochloride at an Electrochemical Sensing Film Constructed by Multiwalled Carbon Nanotubes |
| title_full | Surface-Enhanced Oxidation and Determination of Isothipendyl Hydrochloride at an Electrochemical Sensing Film Constructed by Multiwalled Carbon Nanotubes |
| title_fullStr | Surface-Enhanced Oxidation and Determination of Isothipendyl Hydrochloride at an Electrochemical Sensing Film Constructed by Multiwalled Carbon Nanotubes |
| title_full_unstemmed | Surface-Enhanced Oxidation and Determination of Isothipendyl Hydrochloride at an Electrochemical Sensing Film Constructed by Multiwalled Carbon Nanotubes |
| title_short | Surface-Enhanced Oxidation and Determination of Isothipendyl Hydrochloride at an Electrochemical Sensing Film Constructed by Multiwalled Carbon Nanotubes |
| title_sort | surface enhanced oxidation and determination of isothipendyl hydrochloride at an electrochemical sensing film constructed by multiwalled carbon nanotubes |
| url | http://dx.doi.org/10.1155/2012/875631 |
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