Unveiling the Enigma of Cutaneous Adnexal Tumors: A 2-year Clinicopathological Study in a Tertiary Care Center of the Sub-Himalayan Region
Introduction: Cutaneous adnexal tumors (CATs) are a group of heterogeneous tumors of the pilosebaceous or eccrine-apocrine origin. Specific diagnosis of CATs is difficult to make. We conducted this retrospective study in a tertiary care center to observe the clinical and histopathological features o...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Clinical Dermatology Review |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/cdr.cdr_110_23 |
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| Summary: | Introduction:
Cutaneous adnexal tumors (CATs) are a group of heterogeneous tumors of the pilosebaceous or eccrine-apocrine origin. Specific diagnosis of CATs is difficult to make. We conducted this retrospective study in a tertiary care center to observe the clinical and histopathological features of CATs.
Materials and Methods:
Demographic, clinical features, and histopathologic characteristics of all CATs were collected from records of the dermatology and pathology department over 2 years.
Results:
There were a total of 44 cases of CATs, accounting for 2.8% of total biopsies. The mean age was 41.3636 ± 18.499 years with a female:male ratio of 1.4:1. Head and neck was the most common site involved in 63.64% of cases; involvement of the face was more common than the scalp. Tumors of follicular origin were seen in 45.4%, eccrine in 43.2%, and those of sebaceous origin in 11.3% of cases. Pilomatricoma was the most common CAT of follicular origin and hidradenoma of eccrine origin. There were 6.8% of malignant CATs. Clinical diagnosis correlated with histopathological findings in 22.7% of cases.
Limitations:
Not all cases of CATs were sent for histopathological evaluation so the true incidence of these tumors could not be determined. Histochemistry and immunohistochemistry were not done.
Conclusion:
Making a specific diagnosis of CATs is difficult. A larger number of samples need to be sent for histopathological evaluation so as to sensitize both clinicians and pathologists for a specific diagnosis. |
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| ISSN: | 2542-551X 2542-5528 |