Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series

Background. Basal cell carcinoma (BCC) is the most prevalent skin cancer. Because of its highly vascular characteristic, it is amendable to treatment with pulse dye laser (PDL). The goal of this study is to determine the safety and efficacy of PDL therapy for mostly facial BCCs. Materials and Method...

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Main Authors: Norman Minars, Marianna Blyumin-Karasik
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Skin Cancer
Online Access:http://dx.doi.org/10.1155/2012/286480
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author Norman Minars
Marianna Blyumin-Karasik
author_facet Norman Minars
Marianna Blyumin-Karasik
author_sort Norman Minars
collection DOAJ
description Background. Basal cell carcinoma (BCC) is the most prevalent skin cancer. Because of its highly vascular characteristic, it is amendable to treatment with pulse dye laser (PDL). The goal of this study is to determine the safety and efficacy of PDL therapy for mostly facial BCCs. Materials and Methods. Sixteen men and thirteen women (29 total) with 39 biopsy-proven BCCs were treated with 1–4 PDL (595 nm) therapies at 2–4-week intervals. The treatment parameters included pulse energy of 15 J/cm 2, pulse length of 3 millisecond, with no dynamic cooling, and 7 mm spot size. The age of the patients was 30–90 years (mean 73 years). Response rates were evaluated by the clinical assessments with mean followup of 11 months. Results. Twenty-four patients with thirty-two tumors reached at least three months followup: 24/32 (75%) tumors with complete resolution (mean 3 treatment sessions); 5/32 (16%) tumors recurred; 3/32 (9%) tumors with incomplete responses after four treatments. Minimal side effects and discomfort were experienced by the patients with PDL therapy. Conclusion. PDL is a safe, tolerable, and moderately effective method of treating various BCCs. The ideal niche and standardized settings for PDL treatment of BCCs are yet to be determined.
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spelling doaj-art-3dd437f1176e4872af4844b8a9de39182025-02-03T01:10:52ZengWileyJournal of Skin Cancer2090-29052090-29132012-01-01201210.1155/2012/286480286480Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case SeriesNorman Minars0Marianna Blyumin-Karasik1Minars Dermatology Skin and Laser Center, 4060C Sheridan Street, Hollywood, FL 33021, USAMinars Dermatology Skin and Laser Center, 4060C Sheridan Street, Hollywood, FL 33021, USABackground. Basal cell carcinoma (BCC) is the most prevalent skin cancer. Because of its highly vascular characteristic, it is amendable to treatment with pulse dye laser (PDL). The goal of this study is to determine the safety and efficacy of PDL therapy for mostly facial BCCs. Materials and Methods. Sixteen men and thirteen women (29 total) with 39 biopsy-proven BCCs were treated with 1–4 PDL (595 nm) therapies at 2–4-week intervals. The treatment parameters included pulse energy of 15 J/cm 2, pulse length of 3 millisecond, with no dynamic cooling, and 7 mm spot size. The age of the patients was 30–90 years (mean 73 years). Response rates were evaluated by the clinical assessments with mean followup of 11 months. Results. Twenty-four patients with thirty-two tumors reached at least three months followup: 24/32 (75%) tumors with complete resolution (mean 3 treatment sessions); 5/32 (16%) tumors recurred; 3/32 (9%) tumors with incomplete responses after four treatments. Minimal side effects and discomfort were experienced by the patients with PDL therapy. Conclusion. PDL is a safe, tolerable, and moderately effective method of treating various BCCs. The ideal niche and standardized settings for PDL treatment of BCCs are yet to be determined.http://dx.doi.org/10.1155/2012/286480
spellingShingle Norman Minars
Marianna Blyumin-Karasik
Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series
Journal of Skin Cancer
title Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series
title_full Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series
title_fullStr Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series
title_full_unstemmed Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series
title_short Treatment of Basal Cell Carcinomas with Pulsed Dye Laser: A Case Series
title_sort treatment of basal cell carcinomas with pulsed dye laser a case series
url http://dx.doi.org/10.1155/2012/286480
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