Systemic Endothelial Function in Primary Open-Angle Glaucoma

Objective. We aimed to assess peripheral vascular endothelial function in open-angle glaucoma (POAG) by measuring flow-mediated dilatation (FMD). Materials and Methods. The study included 20 cases with POAG (group 1, mean age 58.68±13.3 years) and 30 healthy individuals (group 2,...

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Bibliographic Details
Main Authors: Mustafa Atas, Hasan Basri Arifoglu, Arzu Seyhan Karatepe Hashas, Bahadır Sarli, Suleyman Demircan, Ayse Ozkose, Altan Goktas
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2014/529082
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Summary:Objective. We aimed to assess peripheral vascular endothelial function in open-angle glaucoma (POAG) by measuring flow-mediated dilatation (FMD). Materials and Methods. The study included 20 cases with POAG (group 1, mean age 58.68±13.3 years) and 30 healthy individuals (group 2, mean age 58.68±13.6 years). In all cases, responses of endothelial function were assessed by a cardiologist through measurement of FMD following brachial artery occlusion. Results. Mean percent of FMD, an indicator of endothelial function, was found to be 11.9±4.2% in group 1 and 12.3±4.4% in group 2 (P=0.86). Conclusion. No impairment in systemic vascular function of cases with POAG suggests that POAG could be a local disorder rather than being a component of systemic disease.
ISSN:2090-004X
2090-0058