Genetic Polymorphisms Associated with Cyclophosphamide Outcome and Risk of Toxicity in Patients with Lupus Nephritis

Genetic Polymorphisms Associated with Cyclophosphamide Outcome and Risk of Toxicity in Patients with Lupus Nephritis

A 6-month cyclophosphamide induction therapy followed by maintenance therapy every three months is the first-line treatment for Class III, IV, and V lupus nephritis. Among the 139 single nucleotide polymorphisms (SNPs) associated with cyclophosphamide, four SNPs, namely rs4244285, rs4802101, rs72545...

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Bibliographic Details
Main Authors: Yen Yen Ari Indrawijaya, Laniyati Hamijoyo, Aluicia Anita Artarini, Maria Immaculata Iwo
Format: Article
Language:English
Published: Interna Publishing 2023-11-01
Series:Acta Medica Indonesiana
Subjects:
Cyclophosphamide
SNP
response
risk of toxicity
Online Access:http://www.actamedindones.org/index.php/ijim/article/view/2432
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