The radiogenomic and spatiogenomic landscapes of glioblastoma and their relationship to oncogenic drivers

The radiogenomic and spatiogenomic landscapes of glioblastoma and their relationship to oncogenic drivers

Abstract Background Glioblastoma is a highly heterogeneous brain tumor, posing challenges for precision therapies and patient stratification in clinical trials. Understanding how genetic mutations influence tumor imaging may improve patient management and treatment outcomes. This study investigates...

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Main Authors: Anahita Fathi Kazerooni, Hamed Akbari, Xiaoju Hu, Vikas Bommineni, Dimitris Grigoriadis, Erik Toorens, Chiharu Sako, Elizabeth Mamourian, Dominique Ballinger, Robyn Sussman, Ashish Singh, Ioannis I. Verginadis, Nadia Dahmane, Constantinos Koumenis, Zev A. Binder, Stephen J. Bagley, Suyash Mohan, Artemis Hatzigeorgiou, Donald M. O’Rourke, Tapan Ganguly, Subhajyoti De, Spyridon Bakas, MacLean P. Nasrallah, Christos Davatzikos
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00767-0
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