Renal Aspects of Peptic Ulcer Pharmacology
Medications to treat peptic ulcer disease are used widely and may have adverse effects on renal function. Similarly, renal dysfunction may alter the pharmacokinetics of this diverse group of medications resulting in dosage adjustments. The older agents, antacids and sucralfate, allow absorption of c...
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Format: | Article |
Language: | English |
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Wiley
1992-01-01
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Series: | Canadian Journal of Gastroenterology |
Online Access: | http://dx.doi.org/10.1155/1992/743457 |
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author | Daniel Muruve Ellen Burgess |
author_facet | Daniel Muruve Ellen Burgess |
author_sort | Daniel Muruve |
collection | DOAJ |
description | Medications to treat peptic ulcer disease are used widely and may have adverse effects on renal function. Similarly, renal dysfunction may alter the pharmacokinetics of this diverse group of medications resulting in dosage adjustments. The older agents, antacids and sucralfate, allow absorption of cations (calcium, magnesium and aluminum) which may result in toxicity. Newer medications (H2 blockers and omeprazole) appear to have fewer side effects and be better tolerated with appropriate dosage adjustments. |
format | Article |
id | doaj-art-3d8baaf174a144c593e87502b7e841f2 |
institution | Kabale University |
issn | 0835-7900 |
language | English |
publishDate | 1992-01-01 |
publisher | Wiley |
record_format | Article |
series | Canadian Journal of Gastroenterology |
spelling | doaj-art-3d8baaf174a144c593e87502b7e841f22025-02-03T01:04:53ZengWileyCanadian Journal of Gastroenterology0835-79001992-01-0161293410.1155/1992/743457Renal Aspects of Peptic Ulcer PharmacologyDaniel Muruve0Ellen Burgess1Department of Medicine, University of Calgary, Calgary, Alberta, CanadaDepartment of Medicine, University of Calgary, Calgary, Alberta, CanadaMedications to treat peptic ulcer disease are used widely and may have adverse effects on renal function. Similarly, renal dysfunction may alter the pharmacokinetics of this diverse group of medications resulting in dosage adjustments. The older agents, antacids and sucralfate, allow absorption of cations (calcium, magnesium and aluminum) which may result in toxicity. Newer medications (H2 blockers and omeprazole) appear to have fewer side effects and be better tolerated with appropriate dosage adjustments.http://dx.doi.org/10.1155/1992/743457 |
spellingShingle | Daniel Muruve Ellen Burgess Renal Aspects of Peptic Ulcer Pharmacology Canadian Journal of Gastroenterology |
title | Renal Aspects of Peptic Ulcer Pharmacology |
title_full | Renal Aspects of Peptic Ulcer Pharmacology |
title_fullStr | Renal Aspects of Peptic Ulcer Pharmacology |
title_full_unstemmed | Renal Aspects of Peptic Ulcer Pharmacology |
title_short | Renal Aspects of Peptic Ulcer Pharmacology |
title_sort | renal aspects of peptic ulcer pharmacology |
url | http://dx.doi.org/10.1155/1992/743457 |
work_keys_str_mv | AT danielmuruve renalaspectsofpepticulcerpharmacology AT ellenburgess renalaspectsofpepticulcerpharmacology |