Toxicity of herbal medications suggested as treatment for COVID‐19: A narrative review

Abstract Objectives In the absence of a definitive cure, herbal medications are gaining increasing popularity in the general public for treatment of coronavirus disease 2019 (COVID‐19). Although many herbal preparations are safe and can be used without complication, serious toxicities do occur. This...

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Main Authors: Michael A. DiPietro, Christopher Mondie
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Journal of the American College of Emergency Physicians Open
Subjects:
Online Access:https://doi.org/10.1002/emp2.12411
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author Michael A. DiPietro
Christopher Mondie
author_facet Michael A. DiPietro
Christopher Mondie
author_sort Michael A. DiPietro
collection DOAJ
description Abstract Objectives In the absence of a definitive cure, herbal medications are gaining increasing popularity in the general public for treatment of coronavirus disease 2019 (COVID‐19). Although many herbal preparations are safe and can be used without complication, serious toxicities do occur. This article focuses on the major characteristics and toxicities of herbal preparations that have been proposed as treatments for COVID‐19. Methods A review was performed focusing on herbal preparations that have gained popularity as potential treatments for COVID‐19. Some of these preparations have been directly recommended by government agencies, whereas others have gained popularity through various other news sources. Results The herbal preparations covered in this paper include the cardiac glycoside oleandrin, plants of the Datura genus, and herbs commonly used in traditional Chinese Medicine including plants of the Aconitum genus, bitter apricot seeds, ephedra, and licorice root. Conclusion Although herbal preparations have been reported to aid in the treatment of COVID‐19 with success, few clinical trials have been performed to evaluate their efficacy and instead rely mainly on in vitro studies and anecdotal reports. Furthermore, many of the herbal preparations suggested carry significant toxicities, and frontline healthcare workers should be aware of the common symptoms and toxidromes that result from these poisonings.
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spelling doaj-art-3d6696e947bd40d4a1f1d1d335e90c2f2025-08-20T03:35:51ZengElsevierJournal of the American College of Emergency Physicians Open2688-11522021-04-0122n/an/a10.1002/emp2.12411Toxicity of herbal medications suggested as treatment for COVID‐19: A narrative reviewMichael A. DiPietro0Christopher Mondie1Department of Emergency Medicine Newark Beth Israel Medical Center Newark New Jersey USADepartment of Emergency Medicine Newark Beth Israel Medical Center Newark New Jersey USAAbstract Objectives In the absence of a definitive cure, herbal medications are gaining increasing popularity in the general public for treatment of coronavirus disease 2019 (COVID‐19). Although many herbal preparations are safe and can be used without complication, serious toxicities do occur. This article focuses on the major characteristics and toxicities of herbal preparations that have been proposed as treatments for COVID‐19. Methods A review was performed focusing on herbal preparations that have gained popularity as potential treatments for COVID‐19. Some of these preparations have been directly recommended by government agencies, whereas others have gained popularity through various other news sources. Results The herbal preparations covered in this paper include the cardiac glycoside oleandrin, plants of the Datura genus, and herbs commonly used in traditional Chinese Medicine including plants of the Aconitum genus, bitter apricot seeds, ephedra, and licorice root. Conclusion Although herbal preparations have been reported to aid in the treatment of COVID‐19 with success, few clinical trials have been performed to evaluate their efficacy and instead rely mainly on in vitro studies and anecdotal reports. Furthermore, many of the herbal preparations suggested carry significant toxicities, and frontline healthcare workers should be aware of the common symptoms and toxidromes that result from these poisonings.https://doi.org/10.1002/emp2.12411Chinese traditionalcomplementary therapiescoronavirusherbalherbal medicinemedicine
spellingShingle Michael A. DiPietro
Christopher Mondie
Toxicity of herbal medications suggested as treatment for COVID‐19: A narrative review
Journal of the American College of Emergency Physicians Open
Chinese traditional
complementary therapies
coronavirus
herbal
herbal medicine
medicine
title Toxicity of herbal medications suggested as treatment for COVID‐19: A narrative review
title_full Toxicity of herbal medications suggested as treatment for COVID‐19: A narrative review
title_fullStr Toxicity of herbal medications suggested as treatment for COVID‐19: A narrative review
title_full_unstemmed Toxicity of herbal medications suggested as treatment for COVID‐19: A narrative review
title_short Toxicity of herbal medications suggested as treatment for COVID‐19: A narrative review
title_sort toxicity of herbal medications suggested as treatment for covid 19 a narrative review
topic Chinese traditional
complementary therapies
coronavirus
herbal
herbal medicine
medicine
url https://doi.org/10.1002/emp2.12411
work_keys_str_mv AT michaeladipietro toxicityofherbalmedicationssuggestedastreatmentforcovid19anarrativereview
AT christophermondie toxicityofherbalmedicationssuggestedastreatmentforcovid19anarrativereview