Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach

While prolactin is most well known for its role in lactation and suppression of reproduction, its physiological functions are quite diverse. There are many etiologies of hyperprolactinemia, including physiologic as well as pathologic causes. Physiologic causes include pregnancy, lactation, sleep-ass...

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Main Authors: Samara Levine, Ozgul Muneyyirci-Delale
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2018/9253083
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author Samara Levine
Ozgul Muneyyirci-Delale
author_facet Samara Levine
Ozgul Muneyyirci-Delale
author_sort Samara Levine
collection DOAJ
description While prolactin is most well known for its role in lactation and suppression of reproduction, its physiological functions are quite diverse. There are many etiologies of hyperprolactinemia, including physiologic as well as pathologic causes. Physiologic causes include pregnancy, lactation, sleep-associated, nipple stimulation and sexual orgasm, chest wall stimulation, or trauma. Stress is also an important physiologic cause of hyperprolactinemia, and its clinical significance is still being explored. This review will provide an overview of prolactin physiology, the role of stress in prolactin secretion, as well as the general clinical approach to hyperprolactinemia.
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series Obstetrics and Gynecology International
spelling doaj-art-3d5aee12743b4c138c8149f48051213d2025-02-03T05:59:54ZengWileyObstetrics and Gynecology International1687-95891687-95972018-01-01201810.1155/2018/92530839253083Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical ApproachSamara Levine0Ozgul Muneyyirci-Delale1Department of Obstetrics and Gynecology, SUNY Downstate Medical Center, Brooklyn, NY, USADepartment of Obstetrics and Gynecology, SUNY Downstate Medical Center, Brooklyn, NY, USAWhile prolactin is most well known for its role in lactation and suppression of reproduction, its physiological functions are quite diverse. There are many etiologies of hyperprolactinemia, including physiologic as well as pathologic causes. Physiologic causes include pregnancy, lactation, sleep-associated, nipple stimulation and sexual orgasm, chest wall stimulation, or trauma. Stress is also an important physiologic cause of hyperprolactinemia, and its clinical significance is still being explored. This review will provide an overview of prolactin physiology, the role of stress in prolactin secretion, as well as the general clinical approach to hyperprolactinemia.http://dx.doi.org/10.1155/2018/9253083
spellingShingle Samara Levine
Ozgul Muneyyirci-Delale
Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach
Obstetrics and Gynecology International
title Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach
title_full Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach
title_fullStr Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach
title_full_unstemmed Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach
title_short Stress-Induced Hyperprolactinemia: Pathophysiology and Clinical Approach
title_sort stress induced hyperprolactinemia pathophysiology and clinical approach
url http://dx.doi.org/10.1155/2018/9253083
work_keys_str_mv AT samaralevine stressinducedhyperprolactinemiapathophysiologyandclinicalapproach
AT ozgulmuneyyircidelale stressinducedhyperprolactinemiapathophysiologyandclinicalapproach