Incidence of iron deficiency anaemia in pregnant women after microcytic hypochromic anaemia: Prospective matched cohort study in Kisangani, Democratic Republic of the Congo
Introduction Iron deficiency anaemia (IDA) in pregnant women is a major public health challenge. The incidence of IDA increases throughout pregnancy, and women who experience it are at a similar risk of recurrence in subsequent pregnancies or even during the same pregnancy. Purpose This st...
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Orapuh, Inc.
2025-08-01
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| author | Martin Soda Jean Kasuyi Lufuluabo Gillon Ilombe Salomon Agasa Batina Pascal Lutumba |
| author_facet | Martin Soda Jean Kasuyi Lufuluabo Gillon Ilombe Salomon Agasa Batina Pascal Lutumba |
| author_sort | Martin Soda |
| collection | DOAJ |
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Introduction
Iron deficiency anaemia (IDA) in pregnant women is a major public health challenge. The incidence of IDA increases throughout pregnancy, and women who experience it are at a similar risk of recurrence in subsequent pregnancies or even during the same pregnancy.
Purpose
This study aimed to determine the incidence of iron deficiency anaemia in pregnant women with microcytic hypochromic anaemia compared with pregnant women with non-microcytic hypochromic anaemia.
Methods
A prospective, open-label, multicentre, matched cohort study was conducted with 11,226 pregnant women, comprising 7,832 (69.77%) with microcytic hypochromic anaemia and 3,394 (30.23%) with non-microcytic hypochromic anaemia. These women were enrolled and monitored for 66 days in antenatal clinics (ANC) across 17 selected health facilities (HF) in Kisangani.
Results
The overall incidence of iron deficiency anaemia was 2.52% (95% CI: 2.47, 2.57) among all pregnant women. Women with microcytic hypochromic anaemia had a higher risk of developing iron deficiency anaemia compared to those with non-microcytic hypochromic anaemia (2.79% vs. 1.91%). Predictors of iron deficiency anaemia in pregnancy included microcytic hypochromic anaemia (aHR = 1.33; 95% CI: 1.26–1.40), age between 20 and 35 years (aHR = 1.19; 95% CI: 1.07–1.34), non-use of insecticide-treated nets (ITNs) (aHR = 1.11; 95% CI: 1.04–1.19), and iron supplementation during pregnancy (aHR = 1.14; 95% CI: 1.06–1.21).
Conclusion
The findings highlight the importance of preventing the progression of anaemia in pregnancy through improved reproductive health services.
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| format | Article |
| id | doaj-art-3d4fc1d033f74ebf902dbdc8e8c78b10 |
| institution | Kabale University |
| issn | 2644-3740 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Orapuh, Inc. |
| record_format | Article |
| series | Orapuh Journal |
| spelling | doaj-art-3d4fc1d033f74ebf902dbdc8e8c78b102025-08-20T04:03:21ZengOrapuh, Inc.Orapuh Journal2644-37402025-08-016810.4314/orapj.v6i8.78Incidence of iron deficiency anaemia in pregnant women after microcytic hypochromic anaemia: Prospective matched cohort study in Kisangani, Democratic Republic of the Congo Martin Soda0Jean Kasuyi Lufuluabo1Gillon Ilombe 2Salomon Agasa Batina3Pascal Lutumba 4Higher Institute of Medical Techniques of Kisangani, Kisangani, Democratic Republic of the CongoHigher Institute of Medical Techniques of Kinshasa, Kinshasa, Democratic Republic of the CongoUniversity of Antwerp, 2000 Antwerp, BelgiumUniversity of Kisangani, Kisangani, Democratic Republic of the CongoHigher Institute of Medical Techniques of Kinshasa, Kinshasa, Democratic Republic of the Congo Introduction Iron deficiency anaemia (IDA) in pregnant women is a major public health challenge. The incidence of IDA increases throughout pregnancy, and women who experience it are at a similar risk of recurrence in subsequent pregnancies or even during the same pregnancy. Purpose This study aimed to determine the incidence of iron deficiency anaemia in pregnant women with microcytic hypochromic anaemia compared with pregnant women with non-microcytic hypochromic anaemia. Methods A prospective, open-label, multicentre, matched cohort study was conducted with 11,226 pregnant women, comprising 7,832 (69.77%) with microcytic hypochromic anaemia and 3,394 (30.23%) with non-microcytic hypochromic anaemia. These women were enrolled and monitored for 66 days in antenatal clinics (ANC) across 17 selected health facilities (HF) in Kisangani. Results The overall incidence of iron deficiency anaemia was 2.52% (95% CI: 2.47, 2.57) among all pregnant women. Women with microcytic hypochromic anaemia had a higher risk of developing iron deficiency anaemia compared to those with non-microcytic hypochromic anaemia (2.79% vs. 1.91%). Predictors of iron deficiency anaemia in pregnancy included microcytic hypochromic anaemia (aHR = 1.33; 95% CI: 1.26–1.40), age between 20 and 35 years (aHR = 1.19; 95% CI: 1.07–1.34), non-use of insecticide-treated nets (ITNs) (aHR = 1.11; 95% CI: 1.04–1.19), and iron supplementation during pregnancy (aHR = 1.14; 95% CI: 1.06–1.21). Conclusion The findings highlight the importance of preventing the progression of anaemia in pregnancy through improved reproductive health services. https://www.orapuh.org/ojs/index.php/orapj/article/view/440Incidenceiron deficiency anaemiapregnant womenmicrocytic hypochromic anaemiaprospective matched cohort study review |
| spellingShingle | Martin Soda Jean Kasuyi Lufuluabo Gillon Ilombe Salomon Agasa Batina Pascal Lutumba Incidence of iron deficiency anaemia in pregnant women after microcytic hypochromic anaemia: Prospective matched cohort study in Kisangani, Democratic Republic of the Congo Orapuh Journal Incidence iron deficiency anaemia pregnant women microcytic hypochromic anaemia prospective matched cohort study review |
| title | Incidence of iron deficiency anaemia in pregnant women after microcytic hypochromic anaemia: Prospective matched cohort study in Kisangani, Democratic Republic of the Congo |
| title_full | Incidence of iron deficiency anaemia in pregnant women after microcytic hypochromic anaemia: Prospective matched cohort study in Kisangani, Democratic Republic of the Congo |
| title_fullStr | Incidence of iron deficiency anaemia in pregnant women after microcytic hypochromic anaemia: Prospective matched cohort study in Kisangani, Democratic Republic of the Congo |
| title_full_unstemmed | Incidence of iron deficiency anaemia in pregnant women after microcytic hypochromic anaemia: Prospective matched cohort study in Kisangani, Democratic Republic of the Congo |
| title_short | Incidence of iron deficiency anaemia in pregnant women after microcytic hypochromic anaemia: Prospective matched cohort study in Kisangani, Democratic Republic of the Congo |
| title_sort | incidence of iron deficiency anaemia in pregnant women after microcytic hypochromic anaemia prospective matched cohort study in kisangani democratic republic of the congo |
| topic | Incidence iron deficiency anaemia pregnant women microcytic hypochromic anaemia prospective matched cohort study review |
| url | https://www.orapuh.org/ojs/index.php/orapj/article/view/440 |
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