Neutrophils Recruited by NKX2‐1 Suppression via Activation of CXCLs/CXCR2 Axis Promote Lung Adenocarcinoma Progression

Neutrophils Recruited by NKX2‐1 Suppression via Activation of CXCLs/CXCR2 Axis Promote Lung Adenocarcinoma Progression

Abstract NK2 Homeobox 1 (NKX2‐1) is a well‐characterized pathological marker that delineates lung adenocarcinoma (LUAD) progression. The advancement of LUAD is influenced by the immune tumor microenvironment through paracrine signaling. However, the involvement of NKX2‐1 in modeling the tumor immune...

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Main Authors: Anita S La'ah, Ping‐Hsing Tsai, Aliaksandr A. Yarmishyn, Lo‐Jei Ching, Chih‐Ying Chen, Yueh Chien, Jerry Chieh‐Yu Chen, Ming‐Long Tsai, Yi‐Chen Chen, Chun Ma, Po‐Kuei Hsu, Yung‐Hung Luo, Yuh‐Min Chen, Guang‐Yuh Chiou, Kai‐Hsi Lu, Wen‐Chang Lin, Yu‐Ting Chou, Mong‐Lien Wang, Shih‐Hwa Chiou
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Advanced Science
Subjects:
cheomkine
lung adenocarccinoma
single cell NGS
tumor microenvironment
Online Access:https://doi.org/10.1002/advs.202400370
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https://doi.org/10.1002/advs.202400370

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