Promotion of SOCS4 in the proliferation and migration of esophageal squamous cell cancer by ubiquitinating SHCBP1 through CRL5

Promotion of SOCS4 in the proliferation and migration of esophageal squamous cell cancer by ubiquitinating SHCBP1 through CRL5

Objective To analyze the role of suppressor of cytokine signaling 4 (SOCS4) in the proliferation and migration of esophageal squamous cell carcinoma (ESCC) , and to explore the relationship between the Cullin-RING ubiquitin E3 ligase 5 (CRL5) and Shc1 SH2.domain binding protein (SHCBP1) . Methods...

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Bibliographic Details
Main Authors: YING Jie, YANG Haifeng, GE Jianxin
Format: Article
Language:zho
Published: The Editorial Department of Chinese Journal of Clinical Research 2025-05-01
Series:Zhongguo linchuang yanjiu
Subjects:
esophageal squamous cell cancer
suppressor of cytokine signaling 4
ubiquitination modification
shc sh2.domain binding protein
Online Access:http://zglcyj.ijournals.cn/zglcyj/ch/reader/create_pdf.aspx?file_no=20250527
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