Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children
Coronavirus disease (COVID-19) is an emergency pandemic with a high mortality rate worldwide. One of its complications in children is developing multisystemic inflammatory syndrome related to cytokine storm. Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist used to suppress th...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2023/8530060 |
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| _version_ | 1832559270141362176 |
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| author | Abdulaziz Alolayan Abdullah S. Aldamegh Azzah Alkhayrat |
| author_facet | Abdulaziz Alolayan Abdullah S. Aldamegh Azzah Alkhayrat |
| author_sort | Abdulaziz Alolayan |
| collection | DOAJ |
| description | Coronavirus disease (COVID-19) is an emergency pandemic with a high mortality rate worldwide. One of its complications in children is developing multisystemic inflammatory syndrome related to cytokine storm. Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist used to suppress the exaggerated inflammatory response in such conditions, and it is potentially lifesaving in a cytokine storm. We present the case of a patient with critical COVID-19 associated with multisystem inflammatory syndrome in children (MIS-C) successfully treated with anakinra intravenous (IV) infusion. |
| format | Article |
| id | doaj-art-3cff685e1af24152a32dc350f96b0ba0 |
| institution | Kabale University |
| issn | 2090-6439 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-3cff685e1af24152a32dc350f96b0ba02025-02-03T01:30:25ZengWileyCase Reports in Critical Care2090-64392023-01-01202310.1155/2023/8530060Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in ChildrenAbdulaziz Alolayan0Abdullah S. Aldamegh1Azzah Alkhayrat2Pharmacy DepartmentPediatrics DepartmentPharmacy DepartmentCoronavirus disease (COVID-19) is an emergency pandemic with a high mortality rate worldwide. One of its complications in children is developing multisystemic inflammatory syndrome related to cytokine storm. Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist used to suppress the exaggerated inflammatory response in such conditions, and it is potentially lifesaving in a cytokine storm. We present the case of a patient with critical COVID-19 associated with multisystem inflammatory syndrome in children (MIS-C) successfully treated with anakinra intravenous (IV) infusion.http://dx.doi.org/10.1155/2023/8530060 |
| spellingShingle | Abdulaziz Alolayan Abdullah S. Aldamegh Azzah Alkhayrat Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children Case Reports in Critical Care |
| title | Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children |
| title_full | Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children |
| title_fullStr | Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children |
| title_full_unstemmed | Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children |
| title_short | Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children |
| title_sort | use of continuous intravenous anakinra infusion in multisystem inflammatory syndrome in children |
| url | http://dx.doi.org/10.1155/2023/8530060 |
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