A Rationale for Going Back to the Future: Use of Disposable Spacers for Pressurised Metered Dose Inhalers

The introduction of pressurised metered dose inhalers (MDIs) in the mid-1950s completely transformed respiratory treatment. Despite decades of availability and healthcare support and development of teaching aids and devices to promote better use, poor pMDI user technique remains a persistent issue....

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Main Authors: Mark Sanders, Ronald Bruin
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Pulmonary Medicine
Online Access:http://dx.doi.org/10.1155/2015/176194
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author Mark Sanders
Ronald Bruin
author_facet Mark Sanders
Ronald Bruin
author_sort Mark Sanders
collection DOAJ
description The introduction of pressurised metered dose inhalers (MDIs) in the mid-1950s completely transformed respiratory treatment. Despite decades of availability and healthcare support and development of teaching aids and devices to promote better use, poor pMDI user technique remains a persistent issue. The main pMDI user aid is the spacer/valved holding chamber (VHC) device. Spacer/chamber features (size, shape, configuration, construction material, and hygiene considerations) can vie with clinical effectiveness (to deliver the same dose as a correctly used pMDI), user convenience, cost, and accessibility. Unsurprisingly, improvised, low-cost alternatives (plastic drink bottles, paper cups, and paper towel rolls) have been pressed into seemingly effective service. A UK law change permitting schools to hold emergency inhalers and spacers has prompted a development project to design a low-cost, user-friendly, disposable, and recyclable spacer. This paper spacer requires neither preuse priming nor washing, and has demonstrated reproducible lung delivery of salbutamol sulphate pMDI, comparable to an industry-standard VHC, an alternative paperboard VHC, and pMDI alone. This new device appears to perform better than these other VHC devices at the low flow rates thought achievable by paediatric patients. The data suggest that this disposable spacer may have a place in the single-use emergency setting.
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spelling doaj-art-3cf4c82eca2b49dd94faabe3d2fc63222025-02-03T00:59:48ZengWileyPulmonary Medicine2090-18362090-18442015-01-01201510.1155/2015/176194176194A Rationale for Going Back to the Future: Use of Disposable Spacers for Pressurised Metered Dose InhalersMark Sanders0Ronald Bruin1Clement Clarke International Limited, Edinburgh Way, Harlow, Essex CM20 2TT, UKClement Clarke International Limited, Edinburgh Way, Harlow, Essex CM20 2TT, UKThe introduction of pressurised metered dose inhalers (MDIs) in the mid-1950s completely transformed respiratory treatment. Despite decades of availability and healthcare support and development of teaching aids and devices to promote better use, poor pMDI user technique remains a persistent issue. The main pMDI user aid is the spacer/valved holding chamber (VHC) device. Spacer/chamber features (size, shape, configuration, construction material, and hygiene considerations) can vie with clinical effectiveness (to deliver the same dose as a correctly used pMDI), user convenience, cost, and accessibility. Unsurprisingly, improvised, low-cost alternatives (plastic drink bottles, paper cups, and paper towel rolls) have been pressed into seemingly effective service. A UK law change permitting schools to hold emergency inhalers and spacers has prompted a development project to design a low-cost, user-friendly, disposable, and recyclable spacer. This paper spacer requires neither preuse priming nor washing, and has demonstrated reproducible lung delivery of salbutamol sulphate pMDI, comparable to an industry-standard VHC, an alternative paperboard VHC, and pMDI alone. This new device appears to perform better than these other VHC devices at the low flow rates thought achievable by paediatric patients. The data suggest that this disposable spacer may have a place in the single-use emergency setting.http://dx.doi.org/10.1155/2015/176194
spellingShingle Mark Sanders
Ronald Bruin
A Rationale for Going Back to the Future: Use of Disposable Spacers for Pressurised Metered Dose Inhalers
Pulmonary Medicine
title A Rationale for Going Back to the Future: Use of Disposable Spacers for Pressurised Metered Dose Inhalers
title_full A Rationale for Going Back to the Future: Use of Disposable Spacers for Pressurised Metered Dose Inhalers
title_fullStr A Rationale for Going Back to the Future: Use of Disposable Spacers for Pressurised Metered Dose Inhalers
title_full_unstemmed A Rationale for Going Back to the Future: Use of Disposable Spacers for Pressurised Metered Dose Inhalers
title_short A Rationale for Going Back to the Future: Use of Disposable Spacers for Pressurised Metered Dose Inhalers
title_sort rationale for going back to the future use of disposable spacers for pressurised metered dose inhalers
url http://dx.doi.org/10.1155/2015/176194
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