Electric Field Analysis of Breast Tumor Cells
An attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is important for effective treatment of tissues. This paper de...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | International Journal of Breast Cancer |
| Online Access: | http://dx.doi.org/10.4061/2011/235926 |
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| _version_ | 1832562725471911936 |
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| author | V. Gowri Sree K. Udayakumar R. Sundararajan |
| author_facet | V. Gowri Sree K. Udayakumar R. Sundararajan |
| author_sort | V. Gowri Sree |
| collection | DOAJ |
| description | An attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is important for effective treatment of tissues. This paper deals with the electric field distribution study of a tissue model using MAXWELL 3D Simulator. Our results indicate that tumor tissue had lower electric field strength compared to normal cells, which makes them susceptible to electrical-pulse-mediated drug delivery. This difference could be due to the altered properties of tumor cells compared to normal cells, and our results corroborate this. |
| format | Article |
| id | doaj-art-3ccd61041fe64e81ba69986f00bde488 |
| institution | Kabale University |
| issn | 2090-3189 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Breast Cancer |
| spelling | doaj-art-3ccd61041fe64e81ba69986f00bde4882025-02-03T01:21:48ZengWileyInternational Journal of Breast Cancer2090-31892011-01-01201110.4061/2011/235926235926Electric Field Analysis of Breast Tumor CellsV. Gowri Sree0K. Udayakumar1R. Sundararajan2Anna University, Chennai 600 025, IndiaAnna University, Chennai 600 025, IndiaPurdue University, West Lafayette, IN 47907, USAAn attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is important for effective treatment of tissues. This paper deals with the electric field distribution study of a tissue model using MAXWELL 3D Simulator. Our results indicate that tumor tissue had lower electric field strength compared to normal cells, which makes them susceptible to electrical-pulse-mediated drug delivery. This difference could be due to the altered properties of tumor cells compared to normal cells, and our results corroborate this.http://dx.doi.org/10.4061/2011/235926 |
| spellingShingle | V. Gowri Sree K. Udayakumar R. Sundararajan Electric Field Analysis of Breast Tumor Cells International Journal of Breast Cancer |
| title | Electric Field Analysis of Breast Tumor Cells |
| title_full | Electric Field Analysis of Breast Tumor Cells |
| title_fullStr | Electric Field Analysis of Breast Tumor Cells |
| title_full_unstemmed | Electric Field Analysis of Breast Tumor Cells |
| title_short | Electric Field Analysis of Breast Tumor Cells |
| title_sort | electric field analysis of breast tumor cells |
| url | http://dx.doi.org/10.4061/2011/235926 |
| work_keys_str_mv | AT vgowrisree electricfieldanalysisofbreasttumorcells AT kudayakumar electricfieldanalysisofbreasttumorcells AT rsundararajan electricfieldanalysisofbreasttumorcells |