Functional Olfactory Nerve Regeneration Demonstrated by Thallium-201 Olfacto-Scintigraphy in Patients with Traumatic Anosmia: A Case Report
Head trauma is one of the most common etiologies of olfactory dysfunction. It is difficult to use either the olfactory function test or magnetic resonance imaging to directly assess the course of damage to olfactory nerves. Thallium-201 (201Tl) olfacto-scintigraphy has been shown to be an able means...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2019/1069741 |
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| author | Rong-San Jiang Yu-Yu Lu |
| author_facet | Rong-San Jiang Yu-Yu Lu |
| author_sort | Rong-San Jiang |
| collection | DOAJ |
| description | Head trauma is one of the most common etiologies of olfactory dysfunction. It is difficult to use either the olfactory function test or magnetic resonance imaging to directly assess the course of damage to olfactory nerves. Thallium-201 (201Tl) olfacto-scintigraphy has been shown to be an able means for objectively assessing the olfactory nerve transport function. It is expected to be used to evaluate olfactory nerve regeneration after damage to the olfactory nerves. However, no such result has been reported. We present a patient who lost his olfactory function after experiencing head trauma. When his olfactory function remained anosmic, a 201Tl olfacto-scintigraphy showed no migration of 201Tl from the nasal mucosa to the olfactory bulb. After treatment with medicines and olfactory training, his olfactory function improved. A second 201Tl olfacto-scintigraphy showed an increased migration of 201Tl from the nasal mucosa to the olfactory bulb. |
| format | Article |
| id | doaj-art-3cc46bbe11054ef7a80920e1e011a833 |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-3cc46bbe11054ef7a80920e1e011a8332025-02-03T05:58:07ZengWileyCase Reports in Otolaryngology2090-67652090-67732019-01-01201910.1155/2019/10697411069741Functional Olfactory Nerve Regeneration Demonstrated by Thallium-201 Olfacto-Scintigraphy in Patients with Traumatic Anosmia: A Case ReportRong-San Jiang0Yu-Yu Lu1Department of Medical Research, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Nuclear Medicine, Taichung Veterans General Hospital, Taichung, TaiwanHead trauma is one of the most common etiologies of olfactory dysfunction. It is difficult to use either the olfactory function test or magnetic resonance imaging to directly assess the course of damage to olfactory nerves. Thallium-201 (201Tl) olfacto-scintigraphy has been shown to be an able means for objectively assessing the olfactory nerve transport function. It is expected to be used to evaluate olfactory nerve regeneration after damage to the olfactory nerves. However, no such result has been reported. We present a patient who lost his olfactory function after experiencing head trauma. When his olfactory function remained anosmic, a 201Tl olfacto-scintigraphy showed no migration of 201Tl from the nasal mucosa to the olfactory bulb. After treatment with medicines and olfactory training, his olfactory function improved. A second 201Tl olfacto-scintigraphy showed an increased migration of 201Tl from the nasal mucosa to the olfactory bulb.http://dx.doi.org/10.1155/2019/1069741 |
| spellingShingle | Rong-San Jiang Yu-Yu Lu Functional Olfactory Nerve Regeneration Demonstrated by Thallium-201 Olfacto-Scintigraphy in Patients with Traumatic Anosmia: A Case Report Case Reports in Otolaryngology |
| title | Functional Olfactory Nerve Regeneration Demonstrated by Thallium-201 Olfacto-Scintigraphy in Patients with Traumatic Anosmia: A Case Report |
| title_full | Functional Olfactory Nerve Regeneration Demonstrated by Thallium-201 Olfacto-Scintigraphy in Patients with Traumatic Anosmia: A Case Report |
| title_fullStr | Functional Olfactory Nerve Regeneration Demonstrated by Thallium-201 Olfacto-Scintigraphy in Patients with Traumatic Anosmia: A Case Report |
| title_full_unstemmed | Functional Olfactory Nerve Regeneration Demonstrated by Thallium-201 Olfacto-Scintigraphy in Patients with Traumatic Anosmia: A Case Report |
| title_short | Functional Olfactory Nerve Regeneration Demonstrated by Thallium-201 Olfacto-Scintigraphy in Patients with Traumatic Anosmia: A Case Report |
| title_sort | functional olfactory nerve regeneration demonstrated by thallium 201 olfacto scintigraphy in patients with traumatic anosmia a case report |
| url | http://dx.doi.org/10.1155/2019/1069741 |
| work_keys_str_mv | AT rongsanjiang functionalolfactorynerveregenerationdemonstratedbythallium201olfactoscintigraphyinpatientswithtraumaticanosmiaacasereport AT yuyulu functionalolfactorynerveregenerationdemonstratedbythallium201olfactoscintigraphyinpatientswithtraumaticanosmiaacasereport |