High Glucose Aggravates the Detrimental Effects of Pancreatic Stellate Cells on Beta-Cell Function
Background and Aims. We here assess the effects of PSCs on β-cell function and apoptosis in vivo and in vitro. Materials and Methods. PSCs were transplanted into Wistar and Goto-Kakizaki (GK) rats. Sixteen weeks after transplantation, β-cell function, apoptosis, and islet fibrosis were assessed. I...
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Main Authors: | Min Zha, Wei Xu, Qing Zhai, Fengfei Li, Bijun Chen, Zilin Sun |
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Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
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Series: | International Journal of Endocrinology |
Online Access: | http://dx.doi.org/10.1155/2014/165612 |
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