Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives
Fibrillar aggregates of human islet amyloid polypeptide, hIAPP, a pathological feature seen in some diabetes patients, are a likely causative agent for pancreatic beta-cell toxicity, leading to a transition from a state of insulin resistance to type II diabetes through the loss of insulin producing...
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Main Authors: | Amit Pithadia, Jeffrey R. Brender, Carol A. Fierke, Ayyalusamy Ramamoorthy |
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Format: | Article |
Language: | English |
Published: |
Wiley
2016-01-01
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Series: | Journal of Diabetes Research |
Online Access: | http://dx.doi.org/10.1155/2016/2046327 |
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