Cerebellar Cathodal Transcranial Direct Stimulation and Performance on a Verb Generation Task: A Replication Study
The role of the cerebellum in cognitive processing is increasingly recognized but still poorly understood. A recent study in this field applied cerebellar Transcranial Direct Current Stimulation (c-tDCS) to the right cerebellum to investigate the role of prefrontal-cerebellar loops in language aspec...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2017/1254615 |
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| author | K. Spielmann R. van der Vliet W. M. E. van de Sandt-Koenderman M. A. Frens G. M. Ribbers R. W. Selles S. van Vugt J. N. van der Geest P. Holland |
| author_facet | K. Spielmann R. van der Vliet W. M. E. van de Sandt-Koenderman M. A. Frens G. M. Ribbers R. W. Selles S. van Vugt J. N. van der Geest P. Holland |
| author_sort | K. Spielmann |
| collection | DOAJ |
| description | The role of the cerebellum in cognitive processing is increasingly recognized but still poorly understood. A recent study in this field applied cerebellar Transcranial Direct Current Stimulation (c-tDCS) to the right cerebellum to investigate the role of prefrontal-cerebellar loops in language aspects of cognition. Results showed that the improvement in participants’ verbal response times on a verb generation task was facilitated immediately after cathodal c-tDCS, compared to anodal or sham c-tDCS. The primary aim of the present study is to replicate these findings and additionally to investigate possible longer term effects. A crossover within-subject design was used, comparing cathodal and sham c-tDCS. The experiment consisted of two visits with an interval of one week. Our results show no direct contribution of cathodal c-tDCS over the cerebellum to language task performance. However, one week later, the group receiving cathodal c-tDCS in the first visit show less improvement and increased variability in their verbal response times during the second visit, compared to the group receiving sham c-tDCS in the first visit. These findings suggest a potential negative effect of c-tDCS and warrant further investigation into long term effects of c-tDCS before undertaking clinical studies with poststroke patients with aphasia. |
| format | Article |
| id | doaj-art-3c71ea141c7c405ca10e1d6404379f91 |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-3c71ea141c7c405ca10e1d6404379f912025-02-03T06:07:25ZengWileyNeural Plasticity2090-59041687-54432017-01-01201710.1155/2017/12546151254615Cerebellar Cathodal Transcranial Direct Stimulation and Performance on a Verb Generation Task: A Replication StudyK. Spielmann0R. van der Vliet1W. M. E. van de Sandt-Koenderman2M. A. Frens3G. M. Ribbers4R. W. Selles5S. van Vugt6J. N. van der Geest7P. Holland8Rijndam Rehabilitation Institute, P.O. Box 23181, 3001 KD Rotterdam, NetherlandsRijndam Rehabilitation Institute, P.O. Box 23181, 3001 KD Rotterdam, NetherlandsRijndam Rehabilitation Institute, P.O. Box 23181, 3001 KD Rotterdam, NetherlandsDepartment of Neuroscience, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, NetherlandsRijndam Rehabilitation Institute, P.O. Box 23181, 3001 KD Rotterdam, NetherlandsRijndam Rehabilitation Institute, P.O. Box 23181, 3001 KD Rotterdam, NetherlandsRijndam Rehabilitation Institute, P.O. Box 23181, 3001 KD Rotterdam, NetherlandsDepartment of Neuroscience, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, NetherlandsDepartment of Neuroscience, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, NetherlandsThe role of the cerebellum in cognitive processing is increasingly recognized but still poorly understood. A recent study in this field applied cerebellar Transcranial Direct Current Stimulation (c-tDCS) to the right cerebellum to investigate the role of prefrontal-cerebellar loops in language aspects of cognition. Results showed that the improvement in participants’ verbal response times on a verb generation task was facilitated immediately after cathodal c-tDCS, compared to anodal or sham c-tDCS. The primary aim of the present study is to replicate these findings and additionally to investigate possible longer term effects. A crossover within-subject design was used, comparing cathodal and sham c-tDCS. The experiment consisted of two visits with an interval of one week. Our results show no direct contribution of cathodal c-tDCS over the cerebellum to language task performance. However, one week later, the group receiving cathodal c-tDCS in the first visit show less improvement and increased variability in their verbal response times during the second visit, compared to the group receiving sham c-tDCS in the first visit. These findings suggest a potential negative effect of c-tDCS and warrant further investigation into long term effects of c-tDCS before undertaking clinical studies with poststroke patients with aphasia.http://dx.doi.org/10.1155/2017/1254615 |
| spellingShingle | K. Spielmann R. van der Vliet W. M. E. van de Sandt-Koenderman M. A. Frens G. M. Ribbers R. W. Selles S. van Vugt J. N. van der Geest P. Holland Cerebellar Cathodal Transcranial Direct Stimulation and Performance on a Verb Generation Task: A Replication Study Neural Plasticity |
| title | Cerebellar Cathodal Transcranial Direct Stimulation and Performance on a Verb Generation Task: A Replication Study |
| title_full | Cerebellar Cathodal Transcranial Direct Stimulation and Performance on a Verb Generation Task: A Replication Study |
| title_fullStr | Cerebellar Cathodal Transcranial Direct Stimulation and Performance on a Verb Generation Task: A Replication Study |
| title_full_unstemmed | Cerebellar Cathodal Transcranial Direct Stimulation and Performance on a Verb Generation Task: A Replication Study |
| title_short | Cerebellar Cathodal Transcranial Direct Stimulation and Performance on a Verb Generation Task: A Replication Study |
| title_sort | cerebellar cathodal transcranial direct stimulation and performance on a verb generation task a replication study |
| url | http://dx.doi.org/10.1155/2017/1254615 |
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