Valine potentiates cefoperazone-sulbactam to kill methicillin-resistant Staphylococcus aureus

Valine potentiates cefoperazone-sulbactam to kill methicillin-resistant Staphylococcus aureus

ABSTRACT Metabolic state-reprogramming approach was extended from Gram-negative bacteria to Gram-positive bacterium methicillin-resistant Staphylococcus aureus (MRSA) for identifying desired reprogramming metabolites to synergize existing antibiotic killing to MRSA. Metabolomics comparison between M...

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Bibliographic Details
Main Authors: Shao-hua Li, Yuan Tao, Zhi-cheng Yang, Huan-zhe Fu, Hui-yin Lin, Xuan-xian Peng, Hui Li
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:mSystems
Subjects:
valine
MRSA
cefoperazone and sulbactam
metabolic reprogramming
antibiotic resistance
Online Access:https://journals.asm.org/doi/10.1128/msystems.01244-24
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