Engineering of L-Plastin Peptide-Loaded Biodegradable Nanoparticles for Sustained Delivery and Suppression of Osteoclast Function In Vitro
We have recently demonstrated that a small molecular weight amino-terminal peptide of L-plastin (10 amino acids; “MARGSVSDEE”) suppressed the phosphorylation of endogenous L-plastin. Therefore, the formation of nascent sealing zones (NSZs) and bone resorption are reduced. The aim of this study was t...
Saved in:
Main Authors: | Sunipa Majumdar, Aniket S. Wadajkar, Hanan Aljohani, Mark A. Reynolds, Anthony J. Kim, Meenakshi Chellaiah |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
|
Series: | International Journal of Cell Biology |
Online Access: | http://dx.doi.org/10.1155/2019/6943986 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Ferrostatin-1 inhibits osteoclast differentiation and prevents osteoporosis by suppressing lipid peroxidation
by: Wenbo Xu, et al.
Published: (2025-01-01) -
Plastin Family of Actin-Bundling Proteins: Its Functions in
Leukocytes, Neurons, Intestines, and Cancer
by: Hiroto Shinomiya
Published: (2012-01-01) -
Pantoprazole Decreases Cell Viability and Function of Human Osteoclasts In Vitro
by: Markus Prause, et al.
Published: (2015-01-01) -
In Vitro Assay to Examine Osteoclast Resorptive Activity Under Estrogen Withdrawal
by: Cara Fiorino, et al.
Published: (2025-01-01) -
Biodegradable and Stimuli-Responsive Nanomaterials for Targeted Drug Delivery in Autoimmune Diseases
by: Nargish Parvin, et al.
Published: (2025-01-01)