Prospects of using C3435T polymorphism in the <i>ABCB1</i> gene encoding P-glycoprotein in personalised medicine

The article reviews scientific literature on C3435T polymorphism in the ABCB1 gene which encodes P-glycoprotein (an ATP-binding cassette transporter which is responsible for energy-dependent transport of substrates across cellular membranes and whose primary role consists in the prevention of penetr...

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Bibliographic Details
Main Authors:	R. E. Kazakov, V. A. Evteev, O. V. Muslimova, I. A. Mazerkina, E. Yu. Demchenkova, E. V. Shikh
Format:	Article
Language:	Russian
Published:	Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2018-02-01
Series:	Регуляторные исследования и экспертиза лекарственных средств
Subjects:	персонализированная медицина генетический полиморфизм p-гликопротеин однонуклеотидные полиморфизмы атф-связывающие кассетные транспортеры personalised medicine genetic polymorphism p-glycoprotein single nucleotide polymorphisms atp-binding cassette transporters
Online Access:	https://www.vedomostincesmp.ru/jour/article/view/143
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Prospects of using C3435T polymorphism in the <i>ABCB1</i> gene encoding P-glycoprotein in personalised medicine

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