Identification of Ocular and Auditory Manifestations of Congenital Rubella Syndrome in Mbingo
Purpose. Congenital rubella syndrome (CRS) is a global cause of preventable hearing impairment, blindness, and intellectual impairment. The present study sought to identify ocular and auditory manifestations of CRS in school-aged children in Mbingo, Cameroon. Design. Cross sectional study. Subjects....
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Telemedicine and Applications |
| Online Access: | http://dx.doi.org/10.1155/2014/981312 |
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| author | Imran Jivraj Chris J. Rudnisky Emmanuel Tambe Graham Tipple Matthew T. S. Tennant |
| author_facet | Imran Jivraj Chris J. Rudnisky Emmanuel Tambe Graham Tipple Matthew T. S. Tennant |
| author_sort | Imran Jivraj |
| collection | DOAJ |
| description | Purpose. Congenital rubella syndrome (CRS) is a global cause of preventable hearing impairment, blindness, and intellectual impairment. The present study sought to identify ocular and auditory manifestations of CRS in school-aged children in Mbingo, Cameroon. Design. Cross sectional study. Subjects. Students at two schools, one for children with hearing impairment, were screened for cataract, congenital glaucoma, and pigmentary retinopathy. Methods. Students underwent seven-field digital fundus photography through a dilated pupil using a Topcon NW200 nonmydriatic camera. Images were assessed by retina specialists in Canada via teleophthalmology. Clinical evidence was integrated to form case definitions for CRS based on Center for Disease Control and Prevention guidelines. Serological evidence of rubella infection was obtained using standardized IgG antibody titers. Main Outcome Measure. Number of probable and suspicious cases of CRS. Results. Between September 2009 and May 2010, 320 students participated. There were 28 (10.2%) probable cases, 104 (37.8%) suspects, and 143 (52.0%) unaffected. Rubella IgG serology was positive in 79 (48.7%) of children with hearing impairment and 11 (7.4%) of children with normal hearing. Conclusions. The present study identified 28 probable cases of CRS. Furthermore, 92.6% of students with normal hearing did not possess rubella IgG antibodies making future cases of CRS likely without intervention. |
| format | Article |
| id | doaj-art-3bc9d714a3a642fdb5b04c67b501b8a3 |
| institution | Kabale University |
| issn | 1687-6415 1687-6423 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Telemedicine and Applications |
| spelling | doaj-art-3bc9d714a3a642fdb5b04c67b501b8a32025-02-03T01:02:12ZengWileyInternational Journal of Telemedicine and Applications1687-64151687-64232014-01-01201410.1155/2014/981312981312Identification of Ocular and Auditory Manifestations of Congenital Rubella Syndrome in MbingoImran Jivraj0Chris J. Rudnisky1Emmanuel Tambe2Graham Tipple3Matthew T. S. Tennant4Department of Ophthalmology, University of Alberta, 10240 Kingsway Avenue NW, Edmonton, AB, T5H 3V9, CanadaDepartment of Ophthalmology, University of Alberta, 10240 Kingsway Avenue NW, Edmonton, AB, T5H 3V9, CanadaDepartment of Ophthalmology, Mbingo Baptist Hospital, CameroonNational Microbiology Laboratory, Public Health Agency of Canada, CanadaDepartment of Ophthalmology, University of Alberta, 10240 Kingsway Avenue NW, Edmonton, AB, T5H 3V9, CanadaPurpose. Congenital rubella syndrome (CRS) is a global cause of preventable hearing impairment, blindness, and intellectual impairment. The present study sought to identify ocular and auditory manifestations of CRS in school-aged children in Mbingo, Cameroon. Design. Cross sectional study. Subjects. Students at two schools, one for children with hearing impairment, were screened for cataract, congenital glaucoma, and pigmentary retinopathy. Methods. Students underwent seven-field digital fundus photography through a dilated pupil using a Topcon NW200 nonmydriatic camera. Images were assessed by retina specialists in Canada via teleophthalmology. Clinical evidence was integrated to form case definitions for CRS based on Center for Disease Control and Prevention guidelines. Serological evidence of rubella infection was obtained using standardized IgG antibody titers. Main Outcome Measure. Number of probable and suspicious cases of CRS. Results. Between September 2009 and May 2010, 320 students participated. There were 28 (10.2%) probable cases, 104 (37.8%) suspects, and 143 (52.0%) unaffected. Rubella IgG serology was positive in 79 (48.7%) of children with hearing impairment and 11 (7.4%) of children with normal hearing. Conclusions. The present study identified 28 probable cases of CRS. Furthermore, 92.6% of students with normal hearing did not possess rubella IgG antibodies making future cases of CRS likely without intervention.http://dx.doi.org/10.1155/2014/981312 |
| spellingShingle | Imran Jivraj Chris J. Rudnisky Emmanuel Tambe Graham Tipple Matthew T. S. Tennant Identification of Ocular and Auditory Manifestations of Congenital Rubella Syndrome in Mbingo International Journal of Telemedicine and Applications |
| title | Identification of Ocular and Auditory Manifestations of Congenital Rubella Syndrome in Mbingo |
| title_full | Identification of Ocular and Auditory Manifestations of Congenital Rubella Syndrome in Mbingo |
| title_fullStr | Identification of Ocular and Auditory Manifestations of Congenital Rubella Syndrome in Mbingo |
| title_full_unstemmed | Identification of Ocular and Auditory Manifestations of Congenital Rubella Syndrome in Mbingo |
| title_short | Identification of Ocular and Auditory Manifestations of Congenital Rubella Syndrome in Mbingo |
| title_sort | identification of ocular and auditory manifestations of congenital rubella syndrome in mbingo |
| url | http://dx.doi.org/10.1155/2014/981312 |
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