Arsenic Exposure and the Induction of Human Cancers
Arsenic is a metalloid, that is, considered to be a human carcinogen. Millions of individuals worldwide are chronically exposed through drinking water, with consequences ranging from acute toxicities to development of malignancies, such as skin and lung cancer. Despite well-known arsenic-related hea...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Journal of Toxicology |
| Online Access: | http://dx.doi.org/10.1155/2011/431287 |
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| _version_ | 1832562353313415168 |
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| author | Victor D. Martinez Emily A. Vucic Daiana D. Becker-Santos Lionel Gil Wan L. Lam |
| author_facet | Victor D. Martinez Emily A. Vucic Daiana D. Becker-Santos Lionel Gil Wan L. Lam |
| author_sort | Victor D. Martinez |
| collection | DOAJ |
| description | Arsenic is a metalloid, that is, considered to be a human carcinogen. Millions of individuals worldwide are chronically exposed through drinking water, with consequences ranging from acute toxicities to development of malignancies, such as skin and lung cancer. Despite well-known arsenic-related health effects, the molecular mechanisms involved are not fully understood; however, the arsenic biotransformation process, which includes methylation changes, is thought to play a key role. This paper explores the relationship of arsenic exposure with cancer development and summarizes current knowledge of the potential mechanisms that may contribute to the neoplastic processes observed in arsenic exposed human populations. |
| format | Article |
| id | doaj-art-3bb8be1b675d4ea397c93cded3223e57 |
| institution | Kabale University |
| issn | 1687-8191 1687-8205 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Toxicology |
| spelling | doaj-art-3bb8be1b675d4ea397c93cded3223e572025-02-03T01:22:49ZengWileyJournal of Toxicology1687-81911687-82052011-01-01201110.1155/2011/431287431287Arsenic Exposure and the Induction of Human CancersVictor D. Martinez0Emily A. Vucic1Daiana D. Becker-Santos2Lionel Gil3Wan L. Lam4Department of Integrative Oncology, British Columbia Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, V5Z 1L3, CanadaDepartment of Integrative Oncology, British Columbia Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, V5Z 1L3, CanadaDepartment of Integrative Oncology, British Columbia Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, V5Z 1L3, CanadaBiomedical Sciences Institute, Faculty of Medicine, University of Chile, Independencia 1027, 8380453 Santiago, ChileDepartment of Integrative Oncology, British Columbia Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, V5Z 1L3, CanadaArsenic is a metalloid, that is, considered to be a human carcinogen. Millions of individuals worldwide are chronically exposed through drinking water, with consequences ranging from acute toxicities to development of malignancies, such as skin and lung cancer. Despite well-known arsenic-related health effects, the molecular mechanisms involved are not fully understood; however, the arsenic biotransformation process, which includes methylation changes, is thought to play a key role. This paper explores the relationship of arsenic exposure with cancer development and summarizes current knowledge of the potential mechanisms that may contribute to the neoplastic processes observed in arsenic exposed human populations.http://dx.doi.org/10.1155/2011/431287 |
| spellingShingle | Victor D. Martinez Emily A. Vucic Daiana D. Becker-Santos Lionel Gil Wan L. Lam Arsenic Exposure and the Induction of Human Cancers Journal of Toxicology |
| title | Arsenic Exposure and the Induction of Human Cancers |
| title_full | Arsenic Exposure and the Induction of Human Cancers |
| title_fullStr | Arsenic Exposure and the Induction of Human Cancers |
| title_full_unstemmed | Arsenic Exposure and the Induction of Human Cancers |
| title_short | Arsenic Exposure and the Induction of Human Cancers |
| title_sort | arsenic exposure and the induction of human cancers |
| url | http://dx.doi.org/10.1155/2011/431287 |
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