Overview of Celiac Disease in Russia: Regional Data and Estimated Prevalence
Celiac disease (CD) is an autoimmune enteropathy triggered by the ingestion of dietary gluten from some cereals mainly in individuals carrying the HLA-DQ2 and/or HLA-DQ8 haplotypes. As an autoimmune disease, CD is manifested in the small intestine in the form of a progressive and reversible inflamma...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2017/2314813 |
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| author | Lyudmila V. Savvateeva Svetlana I. Erdes Anton S. Antishin Andrey A. Zamyatnin |
| author_facet | Lyudmila V. Savvateeva Svetlana I. Erdes Anton S. Antishin Andrey A. Zamyatnin |
| author_sort | Lyudmila V. Savvateeva |
| collection | DOAJ |
| description | Celiac disease (CD) is an autoimmune enteropathy triggered by the ingestion of dietary gluten from some cereals mainly in individuals carrying the HLA-DQ2 and/or HLA-DQ8 haplotypes. As an autoimmune disease, CD is manifested in the small intestine in the form of a progressive and reversible inflammatory lesion due to immune response to self-antigens. Indeed, CD is one of the most challenging medicosocial problems in current gastroenterology. At present, the global CD prevalence is estimated at approximately 1% based on data sent from different locations and available CD screening strategies used. However, it is impossible to estimate global CD prevalence without all the data from the world, including Russia. In this review, we summarize the data on the incidence and prevalence of CD across geographically distinct regions of Russia, which are mostly present in local Russian scientific sources. Our conclusion is that the situation of CD prevalence in Russia is higher than is commonly believed and follows global tendencies that correspond to the epidemiologic situation in Europe, America, and Southwest Asia. |
| format | Article |
| id | doaj-art-3baefd10ae704a48b8cdf7b1a1cb130d |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-3baefd10ae704a48b8cdf7b1a1cb130d2025-02-03T07:25:48ZengWileyJournal of Immunology Research2314-88612314-71562017-01-01201710.1155/2017/23148132314813Overview of Celiac Disease in Russia: Regional Data and Estimated PrevalenceLyudmila V. Savvateeva0Svetlana I. Erdes1Anton S. Antishin2Andrey A. Zamyatnin3Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Moscow 119991, RussiaFaculty of Pediatrics, Sechenov First Moscow State Medical University, Moscow 119991, RussiaFaculty of Pediatrics, Sechenov First Moscow State Medical University, Moscow 119991, RussiaInstitute of Molecular Medicine, Sechenov First Moscow State Medical University, Moscow 119991, RussiaCeliac disease (CD) is an autoimmune enteropathy triggered by the ingestion of dietary gluten from some cereals mainly in individuals carrying the HLA-DQ2 and/or HLA-DQ8 haplotypes. As an autoimmune disease, CD is manifested in the small intestine in the form of a progressive and reversible inflammatory lesion due to immune response to self-antigens. Indeed, CD is one of the most challenging medicosocial problems in current gastroenterology. At present, the global CD prevalence is estimated at approximately 1% based on data sent from different locations and available CD screening strategies used. However, it is impossible to estimate global CD prevalence without all the data from the world, including Russia. In this review, we summarize the data on the incidence and prevalence of CD across geographically distinct regions of Russia, which are mostly present in local Russian scientific sources. Our conclusion is that the situation of CD prevalence in Russia is higher than is commonly believed and follows global tendencies that correspond to the epidemiologic situation in Europe, America, and Southwest Asia.http://dx.doi.org/10.1155/2017/2314813 |
| spellingShingle | Lyudmila V. Savvateeva Svetlana I. Erdes Anton S. Antishin Andrey A. Zamyatnin Overview of Celiac Disease in Russia: Regional Data and Estimated Prevalence Journal of Immunology Research |
| title | Overview of Celiac Disease in Russia: Regional Data and Estimated Prevalence |
| title_full | Overview of Celiac Disease in Russia: Regional Data and Estimated Prevalence |
| title_fullStr | Overview of Celiac Disease in Russia: Regional Data and Estimated Prevalence |
| title_full_unstemmed | Overview of Celiac Disease in Russia: Regional Data and Estimated Prevalence |
| title_short | Overview of Celiac Disease in Russia: Regional Data and Estimated Prevalence |
| title_sort | overview of celiac disease in russia regional data and estimated prevalence |
| url | http://dx.doi.org/10.1155/2017/2314813 |
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