Synergistic Interaction between Metformin and Sulfonylureas on Diclofenac-Induced Antinociception Measured Using the Formalin Test in Rats

BACKGROUND: There is evidence that biguanides and sulfonylureas block diclofenac-induced antinociception (DIA) in rat models. However, little is known about the interaction between these hypoglycemics with respect to DIA.

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Bibliographic Details
Main Author: Mario I Ortiz
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2013/579183
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