Synergistic Interaction between Metformin and Sulfonylureas on Diclofenac-Induced Antinociception Measured Using the Formalin Test in Rats
BACKGROUND: There is evidence that biguanides and sulfonylureas block diclofenac-induced antinociception (DIA) in rat models. However, little is known about the interaction between these hypoglycemics with respect to DIA.
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2013/579183 |
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| _version_ | 1832550205842522112 |
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| author | Mario I Ortiz |
| author_facet | Mario I Ortiz |
| author_sort | Mario I Ortiz |
| collection | DOAJ |
| description | BACKGROUND: There is evidence that biguanides and sulfonylureas block diclofenac-induced antinociception (DIA) in rat models. However, little is known about the interaction between these hypoglycemics with respect to DIA. |
| format | Article |
| id | doaj-art-3ba543204d59474882bc1897caf8a9c8 |
| institution | Kabale University |
| issn | 1203-6765 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-3ba543204d59474882bc1897caf8a9c82025-02-03T06:07:25ZengWileyPain Research and Management1203-67652013-01-0118525325810.1155/2013/579183Synergistic Interaction between Metformin and Sulfonylureas on Diclofenac-Induced Antinociception Measured Using the Formalin Test in RatsMario I Ortiz0Área Académica de Medicina del Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Pachuca, MexicoBACKGROUND: There is evidence that biguanides and sulfonylureas block diclofenac-induced antinociception (DIA) in rat models. However, little is known about the interaction between these hypoglycemics with respect to DIA.http://dx.doi.org/10.1155/2013/579183 |
| spellingShingle | Mario I Ortiz Synergistic Interaction between Metformin and Sulfonylureas on Diclofenac-Induced Antinociception Measured Using the Formalin Test in Rats Pain Research and Management |
| title | Synergistic Interaction between Metformin and Sulfonylureas on Diclofenac-Induced Antinociception Measured Using the Formalin Test in Rats |
| title_full | Synergistic Interaction between Metformin and Sulfonylureas on Diclofenac-Induced Antinociception Measured Using the Formalin Test in Rats |
| title_fullStr | Synergistic Interaction between Metformin and Sulfonylureas on Diclofenac-Induced Antinociception Measured Using the Formalin Test in Rats |
| title_full_unstemmed | Synergistic Interaction between Metformin and Sulfonylureas on Diclofenac-Induced Antinociception Measured Using the Formalin Test in Rats |
| title_short | Synergistic Interaction between Metformin and Sulfonylureas on Diclofenac-Induced Antinociception Measured Using the Formalin Test in Rats |
| title_sort | synergistic interaction between metformin and sulfonylureas on diclofenac induced antinociception measured using the formalin test in rats |
| url | http://dx.doi.org/10.1155/2013/579183 |
| work_keys_str_mv | AT marioiortiz synergisticinteractionbetweenmetforminandsulfonylureasondiclofenacinducedantinociceptionmeasuredusingtheformalintestinrats |